
NCBI . NLM . NIH . GOV {
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Title[redir]:
Extracting a Cellular Hierarchy from High-dimensional Cytometry Data with SPADE - PMC
Description:
Multiparametric single-cell analysis is critical for understanding cellular heterogeneity. Despite recent technological advances in single-cell measurements, methods for analyzing high-dimensional single-cell data are often subjective, labor ...
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Keywords {🔍}
spade, cell, cells, tree, markers, data, analysis, cytometry, doi, types, figure, gating, bone, marrow, number, dataset, clusters, flow, google, scholar, cellular, human, rare, clustering, colored, density, cloud, pubmed, population, nodes, pmc, mouse, functional, downsampling, surface, local, mass, node, highdimensional, article, knowledge, multiple, shown, downsampled, marker, densities, hierarchy, methods, prior, biological,
Topics {✒️}
high-dimensional single-cell data iridium-tagged dna intercalator m-dimensional flow dataset sample student t-test high-dimensional cytometry data high-dimensional space defined gm-csf-induced phosphorylation pmc beta search high-dimensional point cloud density-dependent downsampling scheme spanning-tree progression analysis full space occupied t-cells express tcrβ cell-type-dependent behavior mouse bone marrow high-dimensional dataset bone marrow sample user-selected cell types low-density regions correspond b-cells express b220 human bone marrow supplementary materials included analyzing cytometric data analyzing cytometry data web-based analysis flow cytometry dataset single-cell measurements minimum spanning tree polychromatic flow cytometry robust model-based clustering flow cytometry data single-cell data tpo-induced phosphorylated stat5 nfkb pathway activation mass cytometry dataset dataset contained measurements [google scholar] 5 [google scholar] 16 [google scholar] high cd34 expression single cell increases mass cytometry data l1 distance metric mass cytometry analysis single-cell parameters [2] mutually exclusive expression disease-induced shifts intracellular signal activation united states government established signaling functionalities
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