
NCBI . NLM . NIH . GOV {
}
Title[redir]:
The Role of Autophagy in Cancer: Therapeutic Implications - PMC
Description:
Autophagy is a homeostatic, catabolic degradation process whereby cellular proteins and organelles are engulfed into autophagosomes, digested in lysosomes and recycled to sustain cellular metabolism. Autophagy has dual roles in cancer, acting as ...
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Custom-built
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Traffic Estimate {๐}
What is the average monthly size of ncbi.nlm.nih.gov audience?
๐ Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 6,398,976 visitors per month in the current month.
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Keywords {๐}
autophagy, doi, cancer, cell, google, scholar, pubmed, tumor, cells, pmc, article, free, death, shown, inhibition, inhibitors, stress, apoptosis, phase, hcq, role, cellular, mtor, protein, growth, mtorc, inhibitor, beclin, kinase, induce, mechanism, survival, biol, complex, signaling, proteins, formation, tumorigenesis, treatment, drugs, induction, human, autophagic, senescence, therapeutic, target, pathway, preclinical, combination, drug,
Topics {โ๏ธ}
tnf-related apoptosisโinducing ligand pi3k-mtor inhibitor nvp-bez235 carcinogen-induced lung tumors relapsed/refractory multiple myeloma atg5-atg12-atg16 complex promotes beclin 1-bcl-2/bcl-xl interaction phosphatidylinositol 3-kinase/protein kinase pmc beta search anti-hypertensive drugs verapamil anti-epileptic drug valproic atg4b-lc3 complex reveals castrate-resistant prostate cancer atp-competitive mammalian target diverse anti-cancer therapies receptor tyrosine kinases bcl-2/bcl-xl proteins important nf-kappab mediator cell-based screening assays adaptor protein p62/sequestosome1 diverse anti-cancer drugs dual pi3k-mtor inhibitor stimulate proteosome-mediated degradation pi3k-akt-mtor signaling mtor-independent autophagy pathway er stress-induced cytotoxicity polyglutamine-induced lc3 conversion dna damage-response checkpoints enhanced akt-mtor signaling tsc2/mtorc1 signaling axis autophagy-related stress tolerance apoptosis-defective tumor cells temozolomide-induced cytotoxicity ubiquitin-proteasome pathway substrates lipidated form lc3-ii autophagy-mediated tumor dormancy dose-dependent autophagy inhibition anti-malarial drugs chloroquine death receptor agonists active-site inhibitors enhanced trail-mediated apoptosis p62/sqstm1 binds directly selectively target mtorc1 removing damaged organelles/proteins activating transcription factor-6 myc-induced model bcl-2/bcl-xl rapamycin kinase inhibitor oncogenic transformation confers mol cancer ther dna damaging drugs
Questions {โ}
- Hypoxia-induced autophagy: cell death or cell survival?
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- How much revenue does https://www.google.com/maps/place/8600+Rockville+Pike,+Bethesda,+MD+20894/%4038.9959508, -77.101021,17z/data%3D!3m1!4b1!4m5!3m4!1s0x89b7c95e25765ddb%3A0x19156f88b27635b8!8m2!3d38.9959508! 4d-77.0988323 generate?
- How much does https://www.nlm.nih.gov/web_policies.html earn?
- Discover the revenue of https://www.nih.gov/institutes-nih/nih-office-director/office-communications-public-liaison/freedom-information-act-office
- What are the earnings of https://www.hhs.gov/vulnerability-disclosure-policy/index.html?
- Explore the financials of https://support.nlm.nih.gov/?pagename=cloudpmc-viewer%3Apmc%3Aarticle%3Amanuscript
- https://www.nlm.nih.gov/accessibility.html's total income per month
- https://www.nlm.nih.gov/careers/careers.html's revenue stream
- What's the financial outcome of https://www.nlm.nih.gov/?
- What's the financial intake of https://www.nih.gov/?
- Monthly income for https://www.hhs.gov/
- Monthly income for https://www.usa.gov/
Analytics and Tracking {๐}
- Google Analytics
- Google Analytics 4
- Google Tag Manager
Libraries {๐}
- jQuery
- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {โ๏ธ}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {๐ฆ}
- Ncbi