
NCBI . NLM . NIH . GOV {
}
Title[redir]:
IFI16 is an innate immune sensor for intracellular DNA - PMC
Description:
The detection of intracellular microbial DNA is critical to an appropriate innate immune response, however current knowledge on how such DNA is sensed is limited. Here we identify IFI16, a PYHIN protein, as an intracellular DNA sensor mediating ...
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Keywords {🔍}
dna, cells, ifnβ, doi, mer, fig, ifi, induction, vacv, hsv, response, pubmed, google, scholar, protein, transfected, viral, rna, thp, sting, irf, shown, pmc, activation, sirna, article, role, supplementary, measured, mrna, expression, virus, human, free, μgml, innate, polydadt, immune, gene, intracellular, family, tbk, sensing, bmdms, raw, pyhin, signalling, cytosolic, murine, cytoplasmic,
Topics {✒️}
double-stranded b-form dna interferon-inducible ifi200-family genes tbk1/ikkepsilon-mediated irf activation card/dd/ded domain family nf-κb-dependent genes il-6 nf-κb-dependent gene induction vacv 70mer-induced nf-κb retinoic acid-inducible gene v-raf/mil oncogenes39 ifnβ-inducing vaccinia virus alexa647-labelled secondary antibodies tbk1-irf-3 signaling axis cell-type-specific viral recognition paad/dapin/pyrin domain nf-κb-dependent genes32 interferon-inducible gene ifi16 immobilized anti-myc antibody dna-mediated gene induction pmc beta search ifnβ–stimulating viral dna ifnβ-inducing dna sensors dna-stimulated thp1 cells regulating sting-dependent pathways fitc-labelled hsv-1 60mer fitc-labelled hsv 60mer dsvacv 70mer-induced ifnβ pma-treated thp-1 cells precipitated dna-protein complexes tlr-induced ifnβ expression inflammasome-mediated inflammatory responses vacv 70mer-mediated ifnβ dna-treated thp1 cells interferon-dependent innate immunity inflammasome-related pyrin domains dna-mediated ifnβ induction rig-i-dependent sensing β-actin mrna levels inhibit poxviral-stimulated induction double-stranded rna ifn-inducible genes tank-binding kinase 1 specific labelled oligonucleotide ifi16-mediated ifnβ induction rna polymerase iii transcription factor activation nat immunol abstract hsv-1-induced ifnβ mrna sirna-treated thp-1 cells real-time pcr primers stealth rnai sirnas
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- What's the income of https://www.nlm.nih.gov/careers/careers.html?
- How much does https://www.nlm.nih.gov/ rake in every month?
- Profit of https://www.nih.gov/
- What's the financial gain of https://www.hhs.gov/?
- https://www.usa.gov/'s revenue stream
Analytics and Tracking {📊}
- Google Analytics
- Google Analytics 4
- Google Tag Manager
Libraries {📚}
- jQuery
- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {📦}
- Ncbi