
NCBI . NLM . NIH . GOV {
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Title[redir]:
MRI as a central component of clinical trials analysis in brainstem glioma: a report from the Pediatric Brain Tumor Consortium (PBTC) - PMC
Description:
We report MRI findings from 2 pediatric clinical trials of diffuse intrinsic brainstem glioma (BSG) incorporating concurrent radiation therapy (RT) with molecularly targeted agents (gefitinib and tipifarnib). We determined associations of MRI ...
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Keywords {🔍}
tumor, doi, diffusion, patients, values, volume, brain, imaging, google, scholar, survival, perfusion, pubmed, tumors, enhancement, brainstem, bsg, decrease, pfs, mri, children, study, radiation, therapy, pbtc, images, adc, glioma, treatment, baseline, prert, larger, time, gliomas, diffuse, phase, clinical, median, pediatric, lower, roi, pmc, progression, increased, axial, flair, open, tab, trials, progressionfree,
Topics {✒️}
user-assisted semi-automated software pre-rt versus post-rt diffusion/perfusion-weighted mri valid imaging-based surrogate pmc beta search progression-free survival duration radiation-induced brain injury molecular targeting agents—gefitinib early imaging-based surrogate supratentorial high-grade gliomas post-gadolinium t1 longer progression-free survival gradient echo mode brainstem gliomas—retrospective analysis t1 gadolinium images diffusion-weighted imaging post-rt imaging findings imaging-biology-histology correlations post-rt tumor volumes pre-rt diffusion ratios higher pre-rt volumes post-rt diffusion studies magnetic resonance scans post-rt tumor volume post-rt/drug studies decreased blood flow pre-rt tumor volumes similar pre-rt tvf axial t2 flair combined diffusion-weighted 5-year progression-free survival pre-rt diffusion values pre-rt diffusion ratio diffuse pontine gliomas perfusion mr images apparent diffusion coefficient frontal white matter t2 perfusion techniques flow compensation option diffuse brainstem gliomas axial flair sequences newly diagnosed bsg brain stem gliomas methods study design perfusion imaging consisted blood-brain barrier post-rt imaging diffuse brainstem glioma progression-free survival primary brain tumors
Questions {❓}
- Diffuse brainstem gliomas in children: should we or shouldn't we biopsy?
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