
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Nuclear Receptors in Stem Cells and Their Therapeutic Potential - PMC
Description:
The core transcriptional regulatory circuitries are important for controlling stem cell self-renewal and differentiation. Nuclear receptors provide an ideal model to regulate gene expression in both ligand-dependent and ligand-independent manners. ...
Matching Content Categories {π}
- Science
- Education
- Environment
Content Management System {π}
What CMS is ncbi.nlm.nih.gov built with?
Custom-built
No common CMS systems were detected on Ncbi.nlm.nih.gov, and no known web development framework was identified.
Traffic Estimate {π}
What is the average monthly size of ncbi.nlm.nih.gov audience?
π Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
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How Does Ncbi.nlm.nih.gov Make Money? {πΈ}
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The purpose of some websites isn't monetary gain; they're meant to inform, educate, or foster collaboration. Everyone has unique reasons for building websites. This could be an example. Ncbi.nlm.nih.gov might be plotting its profit, but the way they're doing it isn't detectable yet.
Keywords {π}
stem, doi, cells, cell, neural, embryonic, pubmed, nuclear, google, scholar, tlx, receptor, expression, receptors, pmc, article, human, free, differentiation, adult, mouse, oct, signaling, neurons, reprogramming, nature, pluripotent, proliferation, potential, selfrenewal, gene, ipscs, development, dopaminergic, ligands, acid, genes, treatment, orphan, retinoic, shown, pluripotency, histone, neuronal, motor, nanog, drug, sun, induced, spinal,
Topics {βοΈ}
disrupt tlx-hdac/lsd1 interactions constitutively active Ξ²-catenin wnt/beta-catenin signaling pmc beta search estrogen-related receptor Ξ² stem cell-based therapy tlx-null cells isolated tlx-null cells rescued dosage-sensitive sex reversal stem cell-derived neurons cyclin-dependent kinase inhibitor lesser extent rarΞ²/Ξ± retinoic acid-activated receptor tlx-microrna regulatory loop stem cell-specific expression tlx-mir-9 regulatory loop disease-corrected haematopoietic progenitors early pre-symptomatic phase 000 full-length human ligand-dependent transcription factors brain-derived neurotrophic factor cell fate determination virus-free induction neuronal types induced cell-based therapy neural stem cell retinoic acid receptor orphan nuclear receptor pluripotent stem cells histone deacetylase inhibitor ligand-dependent nuclear receptors neural stem cells histone lysine demethylase embryonic stem cell cell stem cell neural progenitor cells embryonic stem cells neuronal cells derived tlx-expressing cells controlling stem cell phosphoinositide 3-kinase signalling regulates cell numbers turn induces differentiation midbrain neural progenitors murine somatic cells desired cell types proliferation deficiency induced abnormal social behaviors lentiviral vector negative feedback loop
Questions {β}
- New therapeutic target for CNS injury?
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