
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Homeobox transcription factor muscle segment homeobox 2 (Msx2) correlates with good prognosis in breast cancer patients and induces apoptosis in vitro - PMC
Description:
The homeobox-containing transcription factor muscle segment homeobox 2 (Msx2) plays an important role in mammary gland development. However, the clinical implications of Msx2 expression in breast cancer are unclear. The aims of this study were to ...
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Keywords {🔍}
msx, cell, expression, breast, doi, cancer, analysis, lines, cells, pubmed, google, scholar, high, apoptosis, protein, levels, tumours, increased, low, survival, nuclear, mrna, study, tumour, cytoplasmic, figure, cyclin, data, death, pmc, mammary, homeobox, tma, overexpression, prognosis, role, development, line, outcome, poor, van, factor, patients, bmp, staining, article, clinical, mcfa, rbm, found,
Topics {✒️}
hypoxia-inducible factor-2alpha correlates ice-cold phosphate-buffered saline extracellular signal-regulated kinase heat-mediated antigen retrieval swegene/wallenberg consortium north rhodamine-coupled secondary antibody pmc beta search references chen yh proliferation-related ki-67 antigen adenovirus-mediated ectopic expression msx2-expressing cell lines caspase-glo working solution competing interests msx2-overexpressing cell lines supplementary materials included breast cancer-specific survival bmp4-mediated cell death recurrence-free survival methods statistical analysis kaplan-meier survival curves cell type-specific effect license information pmcid mcf10a-msx2 cell lines phosphate-buffered saline full-length msx2 msx2-overexpressing cells showed van de rijn cell line models cardiac neural crest msx2-overexpressing mda-mb-231 primary breast cancer murine mammary gland publisher site pdf large-scale clinical studies cox regression analysis homeobox transcription factor mcf10a cell line invasive breast cancer dna-binding activity invasive ductal carcinomas mouse mammary gland n-terminal arm formalin-fixed paraffin-embedded transcriptomic dataset mining cultured sympathetic neuroblasts human breast cancer kaplan-meier estimates ice-cold 70% ethanol post-migratory proliferation van wijnen aj
Questions {❓}
- Deregulated homeobox gene expression in cancer: cause or consequence?
- How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?
- Prognosis?
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