
NCBI . NLM . NIH . GOV {
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Title[redir]:
The many facets of PPARγ: novel insights for the skeleton - PMC
Description:
Peroxisome proliferator-activated receptor-γ (PPARγ) is a nuclear receptor that functions as a master transcriptional regulator of adipocyte conversion. During PPARγ transactivation, multiple signaling pathways interact with one another, leading to ...
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Keywords {🔍}
pparγ, bone, pubmed, google, scholar, doi, marrow, cells, pmc, cell, article, free, adipogenesis, differentiation, expression, peroxisome, studies, formation, receptor, stem, adipocytes, rosiglitazone, mice, gene, genes, proliferatoractivated, transcriptional, adipocyte, biol, skeletal, transcription, factors, mesenchymal, adiposity, rosen, activation, complex, metabolism, binding, brown, insulin, activity, loss, mscs, effects, mass, tissue, critical, role, osteoblasts,
Topics {✒️}
peroxisome proliferator-activated receptor-γ camkii-tak1/tab2-nlk pathway tgf-β/bmp signalling pathways peroxisome proliferator-activated receptor peroxisome proliferator-activated receptors wnt/β-catenin signaling pathway tak1/tab1/nik cascade ppar-gamma regulates osteoclastogenesis ccaat/enhancer-binding protein ccaat/enhancer binding proteins pmc beta search wnt/beta-catenin signaling repress 3t3-l1 adipogenesis 3t3-l1 adipocyte differentiation cell-autonomous circadian rhythms pmc copyright notice transcription coactivator trap220 early b-cell factor u-33/γ2 cells activated target gene-regulatory regions runt-related transcription factor meal-induced pparγ activation full transcriptional activity pparγ/rxr binding sites marrow-derived cell model lineage-specific transcription factors prdm16/ctbp transcriptional complex rosiglitazone induces decreases pparγ-rxr heterodimer complex tzd-induced bone loss bone marrow-derived mscs med14 tethers mediator rosiglitazone-induced bone loss ppar-gamma function regulates lipid biosynthesis fat cell-specific genes pparγ include srebp-1c inbred mouse strain mesenchymal stem cells mesenchymal stem cell fat-selective enhancers adipogenic program due heterotopic bone formation marrow stromal cells license information pmcid team postdoctoral fellowship suppresses osteoblastogenesis partly adipogenic transcriptional cascade endochondral bone formation ppargamma2 regulates
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