
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Delivery of Cytosolic Components by Autophagic Adapter Protein p62 Endows Autophagosomes with Unique Anti-Microbial Properties - PMC
Description:
Autophagy allows cells to self-digest portions of their own cytoplasm for a multitude of physiological purposes including innate and adaptive immunity functions. In one of its innate immunity manifestations, autophagy is known to contribute to the ...
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Keywords {π}
doi, cells, autophagic, fig, autophagy, fau, phagosomes, pubmed, google, scholar, ubiquitin, mycobacterial, proteins, protein, tuberculosis, rps, killing, cell, pmc, induction, mycobacteria, starvation, raw, article, subjected, colocalization, free, immunity, delivery, organelles, infected, control, hrv, bcg, data, conjugates, biol, ribosomal, peptides, atg, domain, ubiquitinated, degradation, deretic, activity, experiments, cytosolic, media, antibodies, intracellular,
Topics {βοΈ}
lyzm-cre atg5fl/fl system lyzm-cre atg5fl/fl mice atg5fl/fl lyz-cre mice lyzm-cre atg5fl/fl macrophages ulk1-atg13-fip200 complex required pmc beta search atg5-atg12 covalent conjugate beclin 1-phosphatidylinositol-3-kinase complex huntingtin-induced cell death bone-marrow derived macrophages protein-lipid conjugation systems supplementary materials included appreciable bafilomycin-conferred protection adapter molecules p62 ubp3p/bre5p ubiquitin protease microbicidal ubiquitin-derived peptides ubiquitinated-protein aggregate formation polyubiquitinated material appeared tor-mediated autophagy regulation affect nf-ΞΊb expression ubiquitin-free fau nutrient-dependent mtorc1 association supplementary movie m3 unique bactericidal properties p62-dependent process unleashes lc3 recruit p62/sqstm1 ubiquitin-proteasome pathway substrates ifn-Ξ³ induced killing /ml murine ifn-Ξ³ equivalent ribosomal protein scrambled sirna-treated controls antigen cross-presentation cytoplasmic protein aggregates colony forming units mhc ii molecules nih grants a1069345 publisher site pdf interconnected protein-protein human neutrophil peptide-1 p62/sqstm1 binds directly produced free ubiquitin-positive material starvation-induced autophagic killing tor-atg13-atg1 reuses cytosolic components fau antibody-reactive band neo-antimicrobial peptides cytosolic proteins including protein aggregates earmarked protein aggregates toxic
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- Earnings of https://scholar.google.com/scholar_lookup?journal=J%20Biol%20Chem&title=The%20carboxyl%20extension%20of%20a%20ubiquitin-like%20protein%20is%20rat%20ribosomal%20protein%20S30&author=J%20Olvera&author=IG%20Wool&volume=268&publication_year=1993&pages=17967-17974&pmid=8394356&
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- https://scholar.google.com/scholar_lookup?journal=J%20Biol%20Chem&title=p62/SQSTM1%20binds%20directly%20to%20Atg8/LC3%20to%20facilitate%20degradation%20of%20ubiquitinated%20protein%20aggregates%20by%20autophagy&author=S%20Pankiv&author=TH%20Clausen&author=T%20Lamark&author=A%20Brech&author=JA%20Bruun&volume=282&publication_year=2007&pages=24131-24145&pmid=17580304&doi=10.1074/jbc.M702824200&'s revenue stream
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- How much does https://scholar.google.com/scholar_lookup?journal=Curr%20Biol&title=Recognition%20of%20bacteria%20in%20the%20cytosol%20of%20Mammalian%20cells%20by%20the%20ubiquitin%20system&author=AJ%20Perrin&author=X%20Jiang&author=CL%20Birmingham&author=NS%20So&author=JH%20Brumell&volume=14&publication_year=2004&pages=806-811&pmid=15120074&doi=10.1016/j.cub.2004.04.033& pull in?
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- What's the profit of https://scholar.google.com/scholar_lookup?journal=J%20Immunol&title=Autophagy%20is%20essential%20for%20mitochondrial%20clearance%20in%20mature%20T%20lymphocytes&author=HH%20Pua&author=J%20Guo&author=M%20Komatsu&author=YW%20He&volume=182&publication_year=2009&pages=4046-4055&pmid=19299702&doi=10.4049/jimmunol.0801143&?
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- Monthly income for https://scholar.google.com/scholar_lookup?journal=Immunity&title=Innate%20and%20adaptive%20immunity%20through%20autophagy&author=D%20Schmid&author=C%20Munz&volume=27&publication_year=2007&pages=11-21&pmid=17663981&doi=10.1016/j.immuni.2007.07.004&
- What's https://doi.org/10.1034/j.1399-3003.2000.16a20.x's gross income?
- Revenue of https://scholar.google.com/scholar_lookup?journal=Eur%20Respir%20J&title=Antibacterial%20activity%20of%20human%20neutrophil%20peptide-1%20against%20Mycobacterium%20tuberculosis%20H37Rv:%20in%20vitro%20and%20ex%20vivo%20study&author=S%20Sharma&author=I%20Verma&author=GK%20Khuller&volume=16&publication_year=2000&pages=112-117&pmid=10933095&doi=10.1034/j.1399-3003.2000.16a20.x&
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- How much profit is https://scholar.google.com/scholar_lookup?journal=J%20Cell%20Sci&title=The%20N-terminus%20and%20Phe52%20residue%20of%20LC3%20recruit%20p62/SQSTM1%20into%20autophagosomes&author=E%20Shvets&author=E%20Fass&author=R%20Scherz-Shouval&author=Z%20Elazar&volume=121&publication_year=2008&pages=2685-2695&pmid=18653543&doi=10.1242/jcs.026005& making per month?
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- https://doi.org/10.1146/annurev.cellbio.20.010403.114015's total income per month
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- How much does https://scholar.google.com/scholar_lookup?journal=Mol%20Cell&title=JNK1-mediated%20phosphorylation%20of%20Bcl-2%20regulates%20starvation-induced%20autophagy&author=Y%20Wei&author=S%20Pattingre&author=S%20Sinha&author=M%20Bassik&author=B%20Levine&volume=30&publication_year=2008&pages=678-688&pmid=18570871&doi=10.1016/j.molcel.2008.06.001& make?
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- How much does https://doi.org/10.1016/j.immuni.2007.05.022 bring in each month?
- What's the revenue for https://scholar.google.com/scholar_lookup?journal=Immunity&title=Toll-like%20receptor%204%20is%20a%20sensor%20for%20autophagy%20associated%20with%20innate%20immunity&author=Y%20Xu&author=C%20Jagannath&author=XD%20Liu&author=A%20Sharafkhaneh&author=KE%20Kolodziejska&volume=27&publication_year=2007&pages=135-144&pmid=17658277&doi=10.1016/j.immuni.2007.05.022&?
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- Earnings of https://scholar.google.com/scholar_lookup?journal=Curr%20Opin%20Cell%20Biol&title=Toward%20unraveling%20membrane%20biogenesis%20in%20mammalian%20autophagy&author=T%20Yoshimori&author=T%20Noda&volume=20&publication_year=2008&pages=401-407&pmid=18472412&doi=10.1016/j.ceb.2008.03.010&
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- How much income does https://scholar.google.com/scholar_lookup?journal=Cell%20Host%20Microbe&title=Autophagosome-independent%20essential%20function%20for%20the%20autophagy%20protein%20Atg5%20in%20cellular%20immunity%20to%20intracellular%20pathogens&author=Z%20Zhao&author=B%20Fux&author=M%20Goodwin&author=IR%20Dunay&author=D%20Strong&volume=4&publication_year=2008&pages=458-469&pmid=18996346&doi=10.1016/j.chom.2008.10.003& have?
- What's https://doi.org/10.1038/ncb1854's gross income?
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