
NCBI . NLM . NIH . GOV {
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Title[redir]:
The placenta: transcriptional, epigenetic, and physiological integration during development - PMC
Description:
The placenta provides critical transport functions between the maternal and fetal circulations during intrauterine development. Formation of this interface relies on coordinated interactions among transcriptional, epigenetic, and environmental ...
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Keywords {🔍}
doi, google, scholar, pubmed, cell, development, cells, mouse, pmc, article, free, placental, embryonic, differentiation, expression, early, dev, human, gene, placenta, maternal, oxygen, formation, embryos, trophoblast, biol, tgcs, mice, epigenetic, histone, factor, methylation, critical, blastocyst, transcription, transcriptional, stem, required, factors, regulation, tgc, dna, activity, hdac, fetal, form, role, genes, blood, protein,
Topics {✒️}
basic helix-loop-helix ccaat/enhancer–binding protein α polycomb-group gene ezh2 earliest-acting transcription factor pmc beta search decondensed gene-rich regions forkhead box d3–null hif-dependent gene expression estrogen-related receptor β transcription factor ap-2gamma acid-base values early large-scale gene expression mouse i-mfa gene protein adp-ribosyltransferase activity gene-specific dna methylation genome-wide screen identified cell-cycle inhibitors p21 ccaat/enhancer binding proteins protein-free medium multiple-probe fish study insulin-stimulated glucose uptake cellular nad+/nadh ratios pmc copyright notice life-threatening condition eclampsia hif-mediated hypoxia responses cell lineage-specific undermethylation fluid-filled cavity inside lineage-committed progenitors destined single-cell embryos developing late 2-cell–stage embryos nucleosome determines accessibility hypoxia inducible factors mammalian germ-cell development lineage-restricted transcription factors prolyl hydroxylase domain erf-null mice fail id family members marker gene expression cpg-binding protein stem cell fate multiple labyrinth-specific subtypes dnmt3l-null embryos fail histone posttranslational modifications dnmt3a–/–dnmt3b–/– embryos adopt ros-mediated damage fetus/placenta weight ratio arginine n-methyltransferase 1 gcm1 gene expression histone deacetylase activity short-lived extraembryonic structures
Questions {❓}
- Maternal circulation in the first-trimester human placenta–myth or reality?
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