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cells, stat, statmut, patients, naive, fig, memory, pubmed, google, scholar, doi, cell, human, igg, mutations, normal, tangye, switching, cdl, expression, pmc, responses, isotype, immunol, differentiation, response, article, agspecific, free, deficiency, determined, levels, control, adhies, ige, cultured, avery, reduced, iga, donors, vivo, serum, iscs, generation, secretion, igm, signaling, vitro, induced, healthy,

Topics {✒️}

il2rg/common γ chain germinal center common variable immunodeficiency aureus cowan dominant-negative mutations dominant-negative common gamma-chain common gamma chain anti-staphylococcus aureus immunoglobulin +igd+ peripheral blood peripheral blood staphylococcus aureus infections org/cgi/content/full/jem cell line staphylococcus aureus γc/stat3-dependent mechanism alexa fluor 488–anti–phospho-stat5 t-dependent b-cell differentiation alexa fluor 647–anti–phospho-stat1 il-4rα–il-13rα1 complex negative isolation kit germinal centers stat6-dependent interleukin-4-induced genes immunoglobulin-secreting cells persist common form pmc beta search impaired antibody responses hyper-ige syndrome inhibit il-4/stat6–mediated differentiation plasma cell lineage functional antibody deficit ad-hies patients remains plasma-cell differentiation generating ag-specific effector pmc copyright notice hyper-igm syndromes caused long-lived immune responses plasma cell generation heterozygous dn mutations dn stat1 mutations x-linked lymphoproliferative disease mitogen-activated protein kinase salivary ag-specific iga hyper-ige syndromes ag-specific ab early b-cell development jak-stat signaling pathway ag-specific igg produced goat anti–human ig specific jak–stat pathways

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