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org/cgi/content/full/0906048106/dcsupplemental anti-obesity/anti-diabetic metabolic features high-fat-diet-induced obesity adipose tissue-specific ap2 computer-linked infrared sensors crossing flox-atg7 mice map1-lc3 conjugation system pmc beta search half-micro test kit drastically reduced efficiency high-fat diet gained cultured 3t3–l1 preadipocytes differentiating 3t3-l1 cells adipocyte-specific gene expression fatty acid β-oxidation free fatty acid atg7 conditional knockout basal physical activities atg7-deleted white adipocytes 0906048106 adipose-specific deletion high-fat diet starting increased β-oxidation rates increased insulin sensitivity conditional knockout mice atg7−/− primary mefs mutant mice exhibited atg7 knockout mice control atg7 wild-type named autophagy-related genes mutant adipocytes exhibited basal physical activity enhanced insulin sensitivity free fatty acids atg7 knockout adipocytes primary mefs derived control wild-type littermates brown adipose tissue important adipocyte-related genes hormone-induced lipolysis hormone induced lipolysis white adipose tissue insulin secretion function dramatically increased number atg7 flox/flox reduced body weight reduced plasma concentrations primary white adipocytes supporting information online real-time pcr analyses increased cytoplasmic volume

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