
NCBI . NLM . NIH . GOV {
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Title[redir]:
Down-Modulation of Programmed Death 1 Alters Regulatory T Cells and Promotes Experimental Autoimmune Encephalomyelitis - PMC
Description:
The regulatory role of programmed death 1 (PD-1) was investigated in the development of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis. Typical EAE could be induced by immunization without pertussis toxin ...
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Keywords {🔍}
cells, mice, doi, ptx, treg, eae, expression, pubmed, google, scholar, pdko, mmog, cdfoxp, immunization, peptide, immune, preincubated, pmc, naïve, dcs, fig, pbs, immunol, pertussis, suppressive, myelinreactive, induction, absence, days, autoimmune, toxin, vitro, shown, cell, presence, experimental, article, frequency, periphery, conversion, suppression, activation, tolerance, foxp, splenocytes, tgfβ, regulatory, encephalomyelitis, induced, similar,
Topics {✒️}
g-protein-dependent lymphocyte recruitment pd-l1-deficient mice show t-cell suppression assay transforming growth factor-β splenic cd4+foxp3+treg cells myelin oligodendrocyte glycoprotein-specific myelin basic protein-specific myelin proteolipid protein-specific enhanced antigen-specific production anti-cd3/c28 mab blood-brain barrier suggests naive mmog-35–55-specific cd4 pmc beta search long-term memory cells cd4+gfp+pd-1− treg cells cd4+pd-1+gfp+ treg cells cd4+pd-1−gfp+ treg cells antigen-specific treg cells pd-l1 signaling regulates neutralizing anti-pd-1 antibody naïve mmog-35–55-specific cd4 dysfunction activates myelin-reactive facs-sorted cd4+gfp+pd-1+ naïve myelin-specific cd4 pmc copyright notice hcv-specific cd8 exhaustion trigger cns-directed attack anti-cd3 mab activation providing foxp3-gfp mice affect anti-cd3-stimulated mixed lymphocyte proliferation inducing p-selectin expression t-cell-depleted splenocytes mmog-35–55-specific tcr-transgenic adaptive foxp3+cd4+ regulatory eae-resistant mouse strain van noort jm providing pd-1ko mice cd4+foxp3+ treg cells adoptive treg-cell generation pd-1ko mice proliferated list biological laboratories publisher site pdf experimental autoimmune encephalomyelitis pd-1ko mice immunized fulminant spontaneous autoimmunity cd4+gfp+pd-1− cells mixed-cell suspension blood–brain barrier van stipdonk mj
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- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {📦}
- Ncbi