
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Inhibition and Activation by CD244 Depends on CD2 and Phospholipase C-γ1 - PMC
Description:
Regulation by the NK and T cell surface receptor CD244 in mice and humans depends both on engagement at the cell surface by CD48 and intracellular interactions with SAP and EAT-2. Relevance to human disease by manipulating CD244 in mouse models is ...
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Keywords {🔍}
eat, cells, pubmed, google, scholar, doi, fyn, mouse, binding, cell, human, fig, shown, peptide, signaling, immunol, pmc, hybridoma, production, interactions, article, data, plcγ, peptides, surface, ligand, free, tyrosine, tail, itsm, response, inhibitory, engagement, effects, protein, cytoplasmic, lck, positive, sap, phosphorylated, mutant, motifs, function, domain, transduced, humans, affinity, interaction, mice, intracellular,
Topics {✒️}
reprosil-pur c18-aq phase bglii-sali cut plegfp-c1 antigen-specific interleukin-2 production phospholipase c-γ1 nicholas recruit phospholipase c-γ1 immobilized anti-gst mab human phospholipase c-γ 2b4−ve lak cells amino acid substitutions fyn-sh3-sh2 binds sap x-linked proliferative patients undergo post-translational modification x-linked lymphoproliferative disease pmc beta search soluble recombinant protein nickel-agarose affinity chromatography fyn-sh3-sh2 affected binding phycoerythrin-coupled secondary antibodies enzyme-linked immunosorbent assay phospholipase c-γ antigen-specific il-2 production proline-rich peptides based pmc copyright notice anti-rat κ-chain enhanced nk killing soluble fyn sh3-sh2 sap-related adaptor eat-2 amino acid 120 cho iek cells fyn sh3-sh2 binds complex biological systems biotin-qkgpplpraavqpkpphg-cooh cd2-281-305 biotin-hpppppghrsqapshrppppghrvq-cooh cd2-322 antigen-specific il-2 response cd2 including cd2ap/cms peptide protein research src kinases fyn cd48+ve tumors ntb-a-mediated cytotoxicity adaptor protein eat-2 fyn-sh3-sh2 binding protein g-sepharose data-dependent acquisition mode lck-sh3-sh2 binding cd2+ve cells antigen-specific il-2 antibody cross-linking sh3 domain-mediated interactions phosphorylated peptide representing surface plasmon resonance
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