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Keywords {🔍}

doi, fig, gaddb, adult, pubmed, google, scholar, dna, neurons, expression, dentate, ect, demethylation, pmc, neural, cells, neurogenesis, mice, induction, analysis, gyrus, activityinduced, article, science, dendritic, mature, neurosci, free, nlm, specific, proliferation, role, neuronal, brain, activitydependent, growth, ectinduced, values, represent, methylation, regions, bdnf, ncbi, search, epigenetic, plasticity, gene, days, vivo, summary,

Topics {✒️}

org/cgi/content/full/1166859/dc1 references n-methyl-d-aspartate receptor liver-specific fgf-1g promoter brain-derived neurotrophic factor classic activity-induced ieg including activity-dependent neurogenesis activity-dependent adult neurogenesis activity-induced dna demethylation activate methylation-silenced reporters neural activity–induced proliferation activity-dependent neural plasticity developed effective lentivi-ruses activity-induced dendritic development pmc beta search neural activity-induced plasticity classic activity-induced iegs region-specific dna demethylation confirmed ect-induced demethylation gadd45b-dependent demethylation pathway abolished ect-induced gadd45b ect-induced dna demethylation activity-dependent demethylation supplementary materials included sample confocal images ect-induced dendritic growth robust mitogenic activity fgf-1b regulatory regions methylation-specific pcr analysis long-lasting modulation activity-induced proliferation neural activity–induced epigenetic dna modification brain-specific promoter primary hippocampal neurons activity-dependent regulation ect-induced gene expression region-specific demethylation showed specific binding nmdar-dependent induction mature mammalian brain neural progenitor proliferation license information pmcid neurogenic niche signals promote dna demethylation retro-viral labeling dentate granule cells regulatory region ix specific regulatory regions long-standing question neuronal activity

Questions {❓}

• How does transient Gadd45b induction regulate activity-dependent adult neurogenesis over the long-term?

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