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Title[redir]:
An ABC transport system that maintains lipid asymmetry in the Gram-negative outer membrane - PMC
Description:
The outer membranes (OMs) of Gram-negative bacteria have an asymmetric lipid distribution with lipopolysaccharides at the outer leaflet and phospholipids (PLs) at the inner leaflet. This lipid arrangement is essential for the barrier function of the ...
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Keywords {🔍}
doi, mla, plda, pathway, google, scholar, pubmed, outer, fig, cells, lipid, mutants, δmlac, pls, function, increased, pmc, leaflet, transport, coli, article, free, pagp, membrane, levels, data, lps, protein, permeability, mutant, escherichia, suppressor, system, sdsedtas, proteins, cell, genes, mutations, edta, abc, gramnegative, shown, phenotypes, sdsedtar, defect, δplda, bacteria, wildtype, pathways, single,
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org/cgi/content/full/0903229106/dcsupplemental membrane-intrinsic β-barrel enzymes mild-acid hydrolysis procedure phopq-mediated regulation produces pmc beta search free fatty acids putative substrate-binding protein quantitative real time-pcr predicted substrate-binding protein om β-barrel proteins minimal surface-exposed pl cell-free extracts atp-binding cassette ribosomal binding site wild-type sample exhibited stable sds-edtar suppressors 7th acyl chain supporting information online primary virulence factor impacts cell-surface pls disc diffusion assays plda functions downstream retrograde pl transport retrograde pl trafficking [google scholar] 41 supplementary materials included deliver phosphatidic acid sds-edtas profile identical abc transport system hepta-acylated lps molecule destroys surface-exposed pls δmlac sds-edtar suppressors license information pmcid host double membrane abc transport machine gram-negative organisms increased sds-edta sensitivity identical sds-edta sensitivity publisher site pdf gram-negative bacteria partial pl hydrolysis highly conserved pathway manner conceptually analogous protein channel wall major facilitator superfamily plda-mediated suppression constructed single-deletion mutations mla transport system autophagic defense system single mutants displayed
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