
NCBI . NLM . NIH . GOV {
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Title[redir]:
Cysteine Redox Potential Determines Pro-Inflammatory IL-1β Levels - PMC
Description:
Cysteine (Cys) and its disulfide, cystine (CySS) represent the major extracellular thiol/disulfide redox control system. The redox potential (Eh) of Cys/CySS is centered at approximately −80 mV in the plasma of healthy adults, and oxidation of Eh ...
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Keywords {🔍}
ilβ, doi, cyscyss, plasma, redox, cys, levels, oxidized, google, scholar, pubmed, extracellular, cells, potential, cyss, increase, oxidation, tnfα, human, lung, figure, data, mice, ros, analysis, determined, saa, pmc, study, response, inflammation, production, cell, free, shown, cytokine, proinflammatory, control, monocytes, association, gshgssg, saasupplemented, states, jones, thioldisulfide, fold, saaadequate, diet, protein, article,
Topics {✒️}
rabbit polyclonal anti-β-actin secreted pro-il-1β levels il-1r1/myd88 signaling dependent extracellular thiol/disulfide pool increase pro-il-1β levels quantitative real-time pcr pro-inflammatory transcription factors pro-inflammatory cytokine production steady-state redox potential major monocyte-derived cytokine redox-sensitive membrane-bound thiols transforming growth factor-beta extracellular eh cys/cyss pmc beta search female c57bl/6j mice prototypical pro-inflammatory cytokine supercosil lc-nh2 column modulate il-1β production oxidized eh cys/cyss induce pro-il-1β pro-inflammatory cytokine levels preserve eh cys/cyss alphavbeta6 integrin-dependent mechanisms thiol/disulfide control systems thiol/disulfide redox status oxidized cys/cyss redox hmg-coa reductase inhibitors pro-inflammatory cytokine markers eh cys/cyss correlate cys/cyss couple predominates atlanta/emory university community plasma eh cys/cyss eh cys/cyss correlated increased pro-il-1β thiol/disulfide redox parameters endotoxin-induced lung injury intracellular eh gsh/gssg long-term zinc supplementation rapid lc-ftms method cys/cyss redox media lung il-1β levels oxidized extracellular eh cellular eh gsh/gssg endotoxin-induced il-1β il-1β-luciferase construct il-1β mrna levels involve ros-dependent activation reactive oxygen species age-related macular degeneration plasma il-1β levels
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