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Keywords {🔍}

mirnaa, doi, expression, mirnab, mirna, ilβ, rantes, pubmed, google, scholar, cells, release, response, irak, mrna, ilβinduced, mirnas, protein, fig, mimics, regulation, levels, cell, showed, studies, increase, traf, pmc, transcription, effect, action, inflammatory, mechanism, secretion, shown, proteins, determined, ngml, time, microrna, inhibitors, inhibitor, concentration, mediated, involved, concentrations, article, observed, immune, signalling,

Topics {✒️}

fragile-x-mental-retardation-related protein 1 il-1β-induced mirna-146a acted au-rich-element-mediated upregulation tak1/tab1/tab2/tab3 complex c-jun n-terminal kinase il-1β-induced il-8/rantes release il-1β–induced mirna-146a expression il-1β-induced mirna-146a expression bcr-mediated tnf-α production results il-1β-induced il-8 il-1β induced mirna-146a il-1β-induced mirna-146a il-1β–induced irak1 degradation glucose-induced insulin secretion human bronchial epithelial il-1β-induced il-8 il-1β–induced il-8 high il-1β concentrations il-1β-induced increases il-1β–induced increases higher il-1β concentrations increasing il-1β concentrations il-1β–induced responses pmc beta search low il-1β levels il-1β-induced production high il-1β concentration increasing il-1β concentration il-1β-induced response il-1β induced response high il-1β levels il-1β signalling pathway tab il-1β-induced pro-inflammatory transcription factors il-1β-induced increase reverse mirna-122-mediated repression muscle specific mirna-1 mirna-146a/mirna-146b expression il-1β-induced inflammation il-1β stimulation showed il-1β signalling proteins block tnf-α translation bronchial epithelial medium lesser extend mirna-146b respective rt-pcr probes il-1β concentration range rabbit anti-irak1 antibody nf-kappab-dependent induction rt-pcr based approach mirna-induced silencing complex

Questions {❓}

• AU-rich elements and associated factors: are there unifying principles?
• If miRNA-146a does not target either proteins involved in IL-1β signalling or chemokine transcription and secretion, what is the mechanism of action?
• Repression of protein synthesis by miRNAs: how many mechanisms?

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