
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk - PMC
Description:
Loss of imprinting (LOI) of the insulin-like growth factor-II gene (IGF2), leading to abnormal activation of the normally silent maternal allele, is a common human epigenetic population variant associated with a 5-fold increased frequency of ...
Matching Content Categories {๐}
- Science
- Education
- Telecommunications
Content Management System {๐}
What CMS is ncbi.nlm.nih.gov built with?
Custom-built
No common CMS systems were detected on Ncbi.nlm.nih.gov, and no known web development framework was identified.
Traffic Estimate {๐}
What is the average monthly size of ncbi.nlm.nih.gov audience?
๐ Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Ncbi.nlm.nih.gov Make Money? {๐ธ}
We see no obvious way the site makes money.
Earning money isn't the goal of every website; some are designed to offer support or promote social causes. People have different reasons for creating websites. This might be one such reason. Ncbi.nlm.nih.gov might be plotting its profit, but the way they're doing it isn't detectable yet.
Keywords {๐}
loi, doi, mice, cells, igfii, signaling, expression, google, scholar, cell, fold, pubmed, igf, nvpaew, aom, increased, crypts, acf, fig, gene, treated, cancer, sensitivity, showed, genes, activation, receptor, increase, akt, bars, levels, igfr, enhanced, crypt, progenitor, intestinal, model, colon, analysis, vivo, aberrant, significant, compared, number, reduction, data, results, risk, allele, leads,
Topics {โ๏ธ}
org/cgi/content/full/0710359105/dc1 c56bl/6j background carrying 1309/v2ep-tplj-rb3f-ghjl real-time rt-pcr quantitative real-time pcr nvp-aew541 blocks igf-ii igf-ii caused relocation added alongside igf-ii grb2/ras/erk pathways ฮฒ-catenin/tcf4 complex pmc beta search regulating igf-ii silencing mediates igf-ii signaling igf-ii signaling cascade growth factor-mediated transition growth factor-ii gene proliferation-related gene expression igf-ii signaling specifically higher igf-ii doses low accumulated igf-ii igf-ii signaling pathway concurrent epigenetic-genetic model wild-type allele inhibit igf-ii signaling igf-ii pathway blockade igf-ii secreting cells increased igf-ii sensitivity wnt/ฮฒ-catenin signaling igf-ii signaling receptor igf-ii signaling blockade multiple time points laser capture microdissection primary signaling receptor vivo igf-ii blockade signal transduction assays real-time pcr igf-ii levels found iacobuzio-donahue ca mouse embryonic fibroblasts natl cancer inst publisher site pdf supporting information online license information pmcid proliferation-related genes supplementary materials included ๏ฟฝigf-ii addictedโ igf-ii triggered igf-ii causing internally controlled conditions enhances cell proliferation
Questions {โ}
- Do LOI(+) cells have differential sensitivity to IGF-II and the NVP-AEW541?
- How does a group of dividing and differentiating cells in a developing epithelial tissue sense when it has reached the right critical number of similarly differentiated cells?
Social Networks {๐}(6)
External Links {๐}(96)
- See how much https://doi.org/10.1073/pnas.0710359105 makes per month
- What's the revenue for http://www.pnas.org/cgi/content/full/0710359105/DC1?
- Learn how profitable https://doi.org/10.1002/ijc.2910610425 is on a monthly basis
- Learn about the earnings of https://scholar.google.com/scholar_lookup?journal=Int%20J%20Cancer&author=T%20Lamonerie&author=C%20Lavialle&author=H%20Haddada&author=O%20Brison&volume=61&publication_year=1995&pages=587-592&pmid=7759165&doi=10.1002/ijc.2910610425&
- How much revenue does https://doi.org/10.1002/path.1712 generate?
- How much does https://scholar.google.com/scholar_lookup?journal=J%20Pathol&author=E%20Foulstone&author=S%20Prince&author=O%20Zaccheo&author=JL%20Burns&author=J%20Harper&volume=205&publication_year=2005&pages=145-153&pmid=15641016&doi=10.1002/path.1712& generate monthly?
- Explore the financials of https://doi.org/10.1016/s0960-9822(99)80235-8
- How much revenue does https://scholar.google.com/scholar_lookup?journal=Curr%20Biol&author=SM%20Jones&author=R%20Klinghoffer&author=GD%20Prestwich&author=A%20Toker&author=A%20Kazlauskas&volume=9&publication_year=1999&pages=512-521&pmid=10339426&doi=10.1016/s0960-9822(99)80235-8& bring in?
- What's the profit of https://doi.org/10.1038/nm761?
- Monthly income for https://scholar.google.com/scholar_lookup?journal=Nat%20Med&author=J%20Liang&author=J%20Zubovitz&author=T%20Petrocelli&author=R%20Kotchetkov&author=MK%20Connor&volume=8&publication_year=2002&pages=1153-1160&pmid=12244302&doi=10.1038/nm761&
- Income figures for https://doi.org/10.1016/j.semcdb.2004.01.002
- Check the income stats for https://scholar.google.com/scholar_lookup?journal=Semin%20Cell%20Dev%20Biol&author=J%20Downward&volume=15&publication_year=2004&pages=177-182&pmid=15209377&doi=10.1016/j.semcdb.2004.01.002&
- How much revenue does https://doi.org/10.1038/nrc1279 bring in?
- Check the income stats for https://scholar.google.com/scholar_lookup?journal=Nat%20Rev%20Cancer&author=AP%20Feinberg&author=B%20Tycko&volume=4&publication_year=2004&pages=143-153&pmid=14732866&doi=10.1038/nrc1279&
- How much revenue does https://doi.org/10.1126/science.1080902 generate?
- How much revenue does https://scholar.google.com/scholar_lookup?journal=Science&author=H%20Cui&author=M%20Cruz-Correa&author=FM%20Giardiello&author=DF%20Hutcheon&author=DR%20Kafonek&volume=299&publication_year=2003&pages=1753-1755&pmid=12637750&doi=10.1126/science.1080902& produce monthly?
- How profitable is https://doi.org/10.1093/jnci/djh042?
- Get to know what's the income of https://scholar.google.com/scholar_lookup?journal=J%20Natl%20Cancer%20Inst&author=K%20Woodson&author=A%20Flood&author=L%20Green&author=JA%20Tangrea&author=J%20Hanson&volume=96&publication_year=2004&pages=407-410&pmid=14996863&doi=10.1093/jnci/djh042&
- Earnings of https://doi.org/10.1158/0008-5472.CAN-05-2959
- How much does https://scholar.google.com/scholar_lookup?journal=Cancer%20Res&author=A%20Kaneda&author=AP%20Feinberg&volume=65&publication_year=2005&pages=11236-11240&pmid=16357124&doi=10.1158/0008-5472.CAN-05-2959& make?
- How much does https://scholar.google.com/scholar_lookup?journal=Novartis%20Found%20Symp&author=R%20Ohlsson&volume=262&publication_year=2004&pages=108-121&pmid=15562825& rake in every month?
- How much profit does https://doi.org/10.1126/science.1108080 generate?
- What's https://scholar.google.com/scholar_lookup?journal=Science&author=T%20Sakatani&author=A%20Kaneda&author=CA%20Iacobuzio-Donahue&author=MG%20Carter&author=S%20de%20Boom%20Witzel&volume=307&publication_year=2005&pages=1976-1978&pmid=15731405&doi=10.1126/science.1108080&'s gross income?
- What's the profit of https://doi.org/10.1038/375034a0?
- https://scholar.google.com/scholar_lookup?journal=Nature&author=PA%20Leighton&author=RS%20Ingram&author=J%20Eggenschwiler&author=A%20Efstratiadis&author=SM%20Tilghman&volume=375&publication_year=1995&pages=34-39&pmid=7536897&doi=10.1038/375034a0& income
- Check the income stats for https://doi.org/10.1126/science.1350108
- How much income is https://scholar.google.com/scholar_lookup?journal=Science&author=LK%20Su&author=KW%20Kinzler&author=B%20Vogelstein&author=AC%20Preisinger&author=AR%20Moser&volume=256&publication_year=1992&pages=668-670&pmid=1350108&doi=10.1126/science.1350108& earning monthly?
- Learn about the earnings of https://doi.org/10.1016/s1535-6108(04)00051-0
- How much revenue does https://scholar.google.com/scholar_lookup?journal=Cancer%20Cell&author=C%20Garcia-Echeverria&author=MA%20Pearson&author=A%20Marti&author=T%20Meyer&author=J%20Mestan&volume=5&publication_year=2004&pages=231-239&pmid=15050915&doi=10.1016/s1535-6108(04)00051-0& bring in?
- What's the income generated by https://doi.org/10.1093/toxsci/kfi313 each month?
- How profitable is https://scholar.google.com/scholar_lookup?journal=Toxicol%20Sci&author=A%20Bissahoyo&author=RS%20Pearsall&author=K%20Hanlon&author=V%20Amann&author=D%20Hicks&volume=88&publication_year=2005&pages=340-345&pmid=16150884&doi=10.1093/toxsci/kfi313&?
- Financial intake of https://doi.org/10.1146/annurev.cellbio.13.1.293
- What's the total monthly financial gain of https://scholar.google.com/scholar_lookup?journal=Annu%20Rev%20Cell%20Dev%20Biol&author=A%20Dutta&author=SP%20Bell&volume=13&publication_year=1997&pages=293-332&pmid=9442876&doi=10.1146/annurev.cellbio.13.1.293&?
- https://doi.org/10.1016/s0092-8674(00)81322-7's total income per month
- Profit of https://scholar.google.com/scholar_lookup?journal=Cell&author=TR%20Coleman&author=PB%20Carpenter&author=WG%20Dunphy&volume=87&publication_year=1996&pages=53-63&pmid=8858148&doi=10.1016/s0092-8674(00)81322-7&
- How much does https://doi.org/10.1038/375418a0 bring in each month?
- How much does https://scholar.google.com/scholar_lookup?journal=Nature&author=JP%20Chong&author=HM%20Mahbubani&author=CY%20Khoo&author=JJ%20Blow&volume=375&publication_year=1995&pages=418-421&pmid=7760937&doi=10.1038/375418a0& pull in monthly?
- Check the income stats for https://doi.org/10.1038/375421a0
- Revenue of https://scholar.google.com/scholar_lookup?journal=Nature&author=MA%20Madine&author=CY%20Khoo&author=AD%20Mills&author=RA%20Laskey&volume=375&publication_year=1995&pages=421-424&pmid=7760938&doi=10.1038/375421a0&
- How profitable is https://doi.org/10.1016/0092-8674(89)90398-x?
- How much does https://scholar.google.com/scholar_lookup?journal=Cell&author=S%20Smith&author=B%20Stillman&volume=58&publication_year=1989&pages=15-25&pmid=2546672&doi=10.1016/0092-8674(89)90398-x& pull in?
- Get to know https://doi.org/10.1016/s0921-8777(97)00050-5's earnings
- How much profit is https://scholar.google.com/scholar_lookup?journal=Mutat%20Res&author=AE%20Tomkinson&author=ZB%20Mackey&volume=407&publication_year=1998&pages=1-9&pmid=9539976&doi=10.1016/s0921-8777(97)00050-5& making per month?
- What's the profit of https://doi.org/10.1038/ncb813?
- What's the income of https://scholar.google.com/scholar_lookup?journal=Nat%20Cell%20Biol&author=D%20Coverley&author=H%20Laman&author=RA%20Laskey&volume=4&publication_year=2002&pages=523-528&pmid=12080347&doi=10.1038/ncb813&?
- What's the financial outcome of https://doi.org/10.1128/MCB.26.6.2327-2336.2006?
- What's the profit of https://scholar.google.com/scholar_lookup?journal=Mol%20Cell%20Biol&author=P%20Narayan&author=B%20Holt&author=R%20Tosti&author=LP%20Kane&volume=26&publication_year=2006&pages=2327-2336&pmid=16508008&doi=10.1128/MCB.26.6.2327-2336.2006&?
- How much does https://doi.org/10.3181/00379727-213-44046 generate monthly?
- Find out how much https://scholar.google.com/scholar_lookup?journal=Proc%20Soc%20Exp%20Biol%20Med&author=AL%20Gartel&author=MS%20Serfas&author=AL%20Tyner&volume=213&publication_year=1996&pages=138-149&pmid=8931660&doi=10.3181/00379727-213-44046& earns monthly
- Revenue of https://doi.org/10.1038/sj.onc.1204660
- Get to know https://scholar.google.com/scholar_lookup?journal=Oncogene&author=OG%20Morali&author=V%20Delmas&author=R%20Moore&author=C%20Jeanney&author=JP%20Thiery&volume=20&publication_year=2001&pages=4942-4950&pmid=11526479&doi=10.1038/sj.onc.1204660&'s earnings
- How much does https://doi.org/10.1074/jbc.R600015200 make?
- https://scholar.google.com/scholar_lookup?journal=J%20Biol%20Chem&author=MD%20Gordon&author=R%20Nusse&volume=281&publication_year=2006&pages=22429-22433&pmid=16793760&doi=10.1074/jbc.R600015200&'s revenue stream
- What's the financial outcome of https://doi.org/10.1074/jbc.M507582200?
- How much profit is https://scholar.google.com/scholar_lookup?journal=J%20Biol%20Chem&author=A%20Malliri&author=TP%20Rygiel&author=RA%20van%20der%20Kammen&author=JY%20Song&author=R%20Engers&volume=281&publication_year=2006&pages=543-548&pmid=16249175&doi=10.1074/jbc.M507582200& making per month?
- How much revenue does https://doi.org/10.1073/pnas.261574498 produce monthly?
- What's the financial outcome of https://scholar.google.com/scholar_lookup?journal=Proc%20Natl%20Acad%20Sci%20USA&author=D%20Yan&author=M%20Wiesmann&author=M%20Rohan&author=V%20Chan&author=AB%20Jefferson&volume=98&publication_year=2001&pages=14973-14978&pmid=11752446&doi=10.1073/pnas.261574498&?
- How much profit is https://doi.org/10.4161/cc.4.7.1796 making per month?
- How much does https://scholar.google.com/scholar_lookup?journal=Cell%20Cycle&author=PK%20Vogt&author=H%20Jiang&author=M%20Aoki&volume=4&publication_year=2005&pages=908-913&pmid=15917664&doi=10.4161/cc.4.7.1796& net monthly?
- https://scholar.google.com/scholar_lookup?Wang%20CJ,%20Cheong%20R,%20Levchenko%20A.%20Proceeding%20of%2010th%20International%20Conference%20on%20Miniaturized%20Systems%20for%20Chemistry%20and%20Life%20Sciences;%202006.%20(microTAS2006)'s revenue stream
- How much cash flow does https://doi.org/10.1007/s11010-007-9525-3 have monthly?
- Revenue of https://scholar.google.com/scholar_lookup?journal=Mol%20Cell%20Biochem&author=H%20Gao&author=Z%20Yu&author=D%20Bi&author=L%20Jiang&author=Y%20Cui&volume=305&publication_year=2007&pages=35-44&pmid=17577629&doi=10.1007/s11010-007-9525-3&
- What's the total monthly financial gain of https://doi.org/10.1182/blood-2003-08-2955?
- How much does https://scholar.google.com/scholar_lookup?journal=Blood&author=CC%20Zhang&author=HF%20Lodish&volume=103&publication_year=2004&pages=2513-2521&pmid=14592820&doi=10.1182/blood-2003-08-2955& net monthly?
- https://doi.org/10.1128/mcb.19.5.3278's total income per month
- Revenue of https://scholar.google.com/scholar_lookup?journal=Mol%20Cell%20Biol&author=F%20Frasca&author=G%20Pandini&author=P%20Scalia&author=L%20Sciacca&author=R%20Mineo&volume=19&publication_year=1999&pages=3278-3288&pmid=10207053&doi=10.1128/mcb.19.5.3278&
- How much profit does https://doi.org/10.1038/3260 generate?
- Discover the revenue of https://scholar.google.com/scholar_lookup?journal=Nat%20Med&author=H%20Cui&author=IL%20Horon&author=R%20Ohlsson&author=SR%20Hamilton&author=AP%20Feinberg&volume=4&publication_year=1998&pages=1276-1280&pmid=9809551&doi=10.1038/3260&
- How much money does https://doi.org/10.1016/0304-3835(87)90157-1 make?
- https://scholar.google.com/scholar_lookup?journal=Cancer%20Lett&author=RP%20Bird&volume=37&publication_year=1987&pages=147-151&pmid=3677050&doi=10.1016/0304-3835(87)90157-1&'s financial summary
- What's the monthly income of https://doi.org/10.1309/V2EP-TPLJ-RB3F-GHJL?
- Financial intake of https://scholar.google.com/scholar_lookup?journal=Am%20J%20Clin%20Pathol&author=DC%20Snover&author=JR%20Jass&author=C%20Fenoglio-Preiser&author=KP%20Batts&volume=124&publication_year=2005&pages=380-391&pmid=16191506&doi=10.1309/V2EP-TPLJ-RB3F-GHJL&
- How much profit does https://doi.org/10.1016/s1535-6108(04)00054-6 make?
- How much income does https://scholar.google.com/scholar_lookup?journal=Cancer%20Cell&author=D%20LeRoith&author=L%20Helman&volume=5&publication_year=2004&pages=201-202&pmid=15050909&doi=10.1016/s1535-6108(04)00054-6& have?
- What's the income of https://doi.org/10.1056/NEJMoa040583?
- What are the total earnings of https://scholar.google.com/scholar_lookup?journal=N%20Engl%20J%20Med&author=CP%20Cannon&author=E%20Braunwald&author=CH%20McCabe&author=DJ%20Rader&author=JL%20Rouleau&volume=350&publication_year=2004&pages=1495-1504&pmid=15007110&doi=10.1056/NEJMoa040583&?
- What's the revenue for https://doi.org/10.1126/science.1123191?
- How much revenue does https://scholar.google.com/scholar_lookup?journal=Science&author=JQ%20Ling&author=T%20Li&author=JF%20Hu&author=TH%20Vu&author=HL%20Chen&volume=312&publication_year=2006&pages=269-272&pmid=16614224&doi=10.1126/science.1123191& bring in?
- What's the income generated by https://doi.org/10.1159/000090831 each month?
- What's the revenue for https://scholar.google.com/scholar_lookup?journal=Cytogenet%20Genome%20Res&author=A%20Gabory&author=MA%20Ripoche&author=T%20Yoshimizu&author=L%20Dandolo&volume=113&publication_year=2006&pages=188-193&pmid=16575179&doi=10.1159/000090831&?
- https://doi.org/10.1038/nrg1748's total income per month
- Find out how much https://scholar.google.com/scholar_lookup?journal=Nat%20Rev%20Genet&author=AP%20Feinberg&author=R%20Ohlsson&author=S%20Henikoff&volume=7&publication_year=2006&pages=21-33&pmid=16369569&doi=10.1038/nrg1748& earns monthly
- What's the financial intake of https://doi.org/10.1126/science.288.5463.113?
- How much does https://scholar.google.com/scholar_lookup?journal=Science&author=MA%20Unger&author=HP%20Chou&author=T%20Thorsen&author=A%20Scherer&author=SR%20Quake&volume=288&publication_year=2000&pages=113-116&pmid=10753110&doi=10.1126/science.288.5463.113& earn?
- What are the earnings of https://github.com/ncbi?
- What's the profit of https://www.google.com/maps/place/8600+Rockville+Pike,+Bethesda,+MD+20894/%4038.9959508, -77.101021,17z/data%3D!3m1!4b1!4m5!3m4!1s0x89b7c95e25765ddb%3A0x19156f88b27635b8!8m2!3d38.9959508! 4d-77.0988323?
- What's the monthly money flow for https://www.nlm.nih.gov/web_policies.html?
- How much does https://www.nih.gov/institutes-nih/nih-office-director/office-communications-public-liaison/freedom-information-act-office pull in?
- Monthly income for https://www.hhs.gov/vulnerability-disclosure-policy/index.html
- Financial intake of https://support.nlm.nih.gov/?pagename=cloudpmc-viewer%3Apmc%3Aarticle%3Ajournal
- What's https://www.nlm.nih.gov/accessibility.html's gross income?
- How much revenue does https://www.nlm.nih.gov/careers/careers.html produce monthly?
- What's the financial outcome of https://www.nlm.nih.gov/?
- Find out how much https://www.nih.gov/ earns monthly
- Revenue of https://www.hhs.gov/
- How much does https://www.usa.gov/ make?
Analytics and Tracking {๐}
- Google Analytics
- Google Analytics 4
- Google Tag Manager
Libraries {๐}
- jQuery
- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {โ๏ธ}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {๐ฆ}
- Ncbi