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Title[redir]:
A phase II trial with rosiglitazone in liposarcoma patients - PMC
Description:
Agents of the thiazolidinedione drug family can terminally differentiate human liposarcoma cells in vitro by activating genes responsible for lipocyte differentiation. One study has shown clinical activity of troglitazone treatment in liposarcoma ...
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Keywords {π}
patients, treatment, pparΞ³, liposarcoma, google, scholar, pubmed, doi, rosiglitazone, months, liposarcomas, cancer, cell, patient, human, clinical, gene, pmc, differentiation, molecular, receptor, expression, tumour, study, tontonoz, gamma, nlm, cells, troglitazone, peroxisome, proliferatoractivated, spiegelman, level, analysis, myxoidround, fletcher, ncbi, search, genes, biological, adipsin, protein, myxoid, translocation, fusion, activation, weeks, performed, probe, trial,
Topics {βοΈ}
peroxisome proliferator-activated receptor-Ξ³ peroxisome-proliferator activated receptor-gamma peroxisome proliferator-activated receptors pax8-ppargamma1 fusion oncogene tls-chop fusion protein pmc beta search ews-chop fusion transcript ultrasound-guided needle biopsy lipid-activated transcription factor publisher site pdf primary tumour sample inhibit tumour growth myxoid/round cell subtypes license information pmcid van den bh high affinity ligand myxoid/round cell liposarcomas references antonescu cr rna-binding protein soft tissue simulators tissue-specific regulator solid tumor differentiation cellular proliferation rates human colon cancer united states government giant marker chromosomes chromosomal region 12q dei tos spring-driven device quantify mrna levels glyceraldehyde-3-phosphate dehydrogenase utilising standard procedures g-banded chromosomes increasingly receiving attention elevated liver transaminases fundamental biologic alterations phosphoenolpyruvate carboxykinase gene tumour volume increase myxoid/round cell human genetic nomenclature metastastic colon cancer sporadic colon carcinomas round cell liposarcoma complete adipocytic phenotype specific antitumoral target smith-oliver ta de la ca pmc disclaimer phase ii trial histologically confirmed liposarcoma
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