NCBI . NLM . NIH . GOV {
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Title[redir]:
IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel - PMC
Description:
Neuromyelitis optica (NMO) is an inflammatory demyelinating disease that selectively affects optic nerves and spinal cord. It is considered a severe variant of multiple sclerosis (MS), and frequently is misdiagnosed as MS, but prognosis and optimal ...
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Keywords {🔍}
igg, patients, nmo, aqp, nmoigg, google, scholar, doi, pubmed, brain, cells, water, aquaporin, gfpaqp, pmc, channel, mice, cns, mouse, tissues, sera, binds, transfected, serum, protein, rabbit, control, human, cell, hek, gfp, neuromyelitis, optica, nlm, lennon, article, disease, lesions, kidney, free, multiple, sclerosis, inflammatory, barrier, fig, distribution, lysates, molecular, neurology, ncbi,
Topics {✒️}
rhodamine-conjugated anti–rabbit igg fluorescein-conjugated anti-human igg goat anti–rabbit igg goat anti–human igg distal urine-collecting tubules rabbit anti-aqp4–igg pmc beta search wild-type control mice asian optic-spinal form pure optic-spinal form wild-type brain tissue aqp4-igg captured gfp-aqp4 transgenic aqp4-null mice pmc copyright notice nmo-igg binds selectively nmo-igg positive sera aqp4-null mouse brain aqp4-specific rabbit igg rabbit aqp4-specific igg disease-specific microbial antigen plasmids encoding gfp-aqp4 nmo-igg bound prominently antigen-specific igg molecules dystrophin-null transgenic mice aqp4-transfected cells intensely anti–rabbit igg igg captured α-syntrophin gfp-aqp4–transfected cells human embryonic kidney publisher site pdf license information pmcid distal collecting tubules mouse cerebellar cortex mouse monoclonal iggs astrocytic foot processes autoimmune autonomic neuropathy control human igg anti-gfp–igg aqp4-null mice endothelial tight junctions adult mouse cerebellum zealand white rabbit normal rabbit serum water channel protein tissue water homeostasis reactive astrocytes related predominant water channel igg-mediated dysregulation disease modifying therapies prototype immunopharmacological disease
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