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Title[redir]:
CCR7 Signals Are Essential for Cortex–Medulla Migration of Developing Thymocytes - PMC
Description:
Upon TCR-mediated positive selection, developing thymocytes relocate within the thymus from the cortex to the medulla for further differentiation and selection. However, it is unknown how this cortex–medulla migration of thymocytes is controlled and ...
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Keywords {🔍}
mice, thymocytes, ccr, cells, thymus, medulla, cell, fig, pubmed, google, scholar, medullary, thymic, doi, signals, cortex, adult, mature, migration, mouse, newborn, control, results, pltplt, selection, analysis, transgenic, thymuses, ccrldeficient, defective, cdcd, epithelial, expression, ccrdeficient, staining, positive, cortical, ccrl, stained, regions, immunol, mutant, export, negative, tcr, surface, shown, sections, profiles, pmc,
Topics {✒️}
fitc-conjugated anti–rabbit ig specific pathogen-free conditions lympho-epithelial cross talk class ii mhc–restricted apc-labeled anti-cd4 antibody pe-labeled anti-cd8 antibody sphingosine-1–phosphate–mediated chemotaxis mhc-deficient mice exhibited null selecting h-2k/ anti-tcr antibody restores positively selecting h-2k/ anti-fitc magnetic beads t-lymphocyte-specific homing ccr7l-deficient plt/plt mice 2c-tcr transgenic mice pmc beta search x-ray irradiation system pmc copyright notice ccr7 signal–deficient mice ccl19–ig fusion protein ccr7l-deficient mice showed alexa 488–conjugated anti-cd4 alexa 546–conjugated anti-cd8 fitc-labeled anti-cd3 protein–coupled receptor signals sjl-ptprca congenic mice radiation-resistant sp thymocytes sphingosine-1–phosphate receptor signals hy-tcr transgenic mice ccr7-deficient mice contained tcr-mediated positive selection bone marrow chimeras pma/ionomycin-stimulated dp thymocytes transgenic tcr-expressing cells fitc-conjugated anti-cd45 class ii molecules wt donor–reconstituted group publisher site pdf newborn ccr7-deficient mice ko donor–reconstituted group plt/plt mice deficient ccl19-ig staining profiles newborn plt/plt mice adult ccr7-deficient mice tcr-mediated elevation anti-tcrβ antibody ccr7-expressing mature thymocytes monoclonal antibody directed mutant mice showed crossing mhc class
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