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Keywords {🔍}

doi, tumor, cells, mice, cflip, apoptosis, pubmed, google, scholar, cell, fig, tumors, ctl, expression, escape, vivo, vitro, cytotoxicity, response, arflip, shown, death, data, pmc, immune, murine, pathway, results, mffliplow, medema, immunity, cdinduced, wildtype, perforin, growth, overexpression, pko, mffliphigh, krammer, immunol, perforindependent, ctls, determined, injected, arvector, peter, nlm, sensitivity, line, antibody,

Topics {✒️}

called casper/iflice/flame-1/cash/clarp/mrit/usurpin [3h]thymidine-labeled target cells fas/fas ligand–mediated cytotoxicity mutant ej-ras oncogenes il-1β–converting enzyme fadd-homologous ice/ced-3 bcl-xl acts downstream death-inducing signalling complex death-inducing signaling complex mutant ej-ras–transfected pmc beta search fmr-mulv gagleader sequence prolonged ctl–target interactions cytolytic t-cell cytotoxicity cflip-overexpressing tumor ar6–flip mort1/fadd-interacting protease van den broek anti–flag-m2 antibody anti-flag m2 antibody ctl–target interaction shifts pmc copyright notice ligand-expressing tumor cells anti-cd95–triggered apoptosis ctl-induced dna fragmentation cd95-mediated apoptosis constitutes include cd95-induced apoptosis block cd95-induced apoptosis cd95-dependent apoptosis constitutes inhibit ctl-mediated lysis e1a-specific ctl response lyse e1a-expressing mecs anti-tumor ctl immunity fas-based lytic pathways publisher site pdf tumor-specific ctl clones circles represent mf-fliplow squares represent mf-fliphigh virus-specific ctls 18 ar6–flip tumor grows eradicate mf-fliphigh tumors wild-type mice challenged cflip-overexpressing tumors escape anti-flag antibody activation-induced cell death [3h]thymidine retention growing mf-fliplow tumors cell–dependent immune response escape cd95-dependent cytotoxicity cd95l-expressing mecs mice developed progressively

Questions {❓}

• Lymphocyte apoptosis induced by CD95 (APO-1/Fas)ligand-expressing tumor cells—a mechanism of immune evasion?

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