
NCBI . NLM . NIH . GOV {
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Title[redir]:
Granulocyte Macrophage Colony-Stimulating Factor: A New Putative Therapeutic Target in Multiple Sclerosis - PMC
Description:
Experimental autoimmune encephalomyelitis (EAE), a model for multiple sclerosis, can be induced by immunization with a number of myelin antigens. In particular, myelin oligodendrocyte glycoprotein, a central nervous system (CNS)-specific antigen ...
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Keywords {🔍}
mice, gmcsf, doi, google, scholar, pubmed, cells, cns, disease, eae, mog, clinical, myelin, cell, response, fig, immunol, experimental, inflammatory, lesions, autoimmune, day, encephalomyelitis, factor, colonystimulating, role, pmc, multiple, rgmcsf, peptide, treatment, treated, immunization, inflammation, shown, granulocytemacrophage, immune, activation, expression, antigmcsf, oligodendrocyte, protein, macrophages, isotype, sclerosis, article, central, free, bernard, glycoprotein,
Topics {✒️}
granulocyte-macrophage colony-stimulating factor granulocyte/macrophage colony-stimulating factor slow-acting anti-rheumatic drugs anti–gm-csf mab showed eae-susceptible nod/lt background nod/lt gm-csf−/− mice transforming growth factor-β1 rgm-csf-treated mice showed anti-granulocyte antibodies inhibits susceptible nod/lt background contact-dependent macrophage cytotoxicity strong th1-inducing capacity anti–gm-csf–treated mice anti-murine β-galactosidase pmc beta search murine collagen-induced arthritis gm-csf–deficient mice anti-inflammatory agents interleukin-4 colony-stimulating factors colony stimulating factors rgm-csf–treated wt mice anti–gm-csf mab pmc copyright notice nod/lt wild-type animal ethics committee gm-csf−/− mice proliferated results gm-csf−/− mice adhesion-promoting surface glycoproteins nod/lt mice develop show exacerbated susceptibility listeria monocytogenes-infected mice cell–mediated immune responses mouse anti-mog mab mog-specific ig determination gm-csf inhibition studies hematopoietic growth factor kerlero de rosbo multiple sclerosis cross-react cns-specific antigen expressed mog-specific immune response total mog-specific igg anti-gm-csf treatment mhc class ii gm-csf–deficient rgm-csf accelerates onset transgenic mice expressing anti–gm-csf prevented mog-specific proliferative response macrophage-depleted mice mog35–55 peptide-coated plates
Questions {❓}
- Do antibodies to myelin basic protein isolated from multiple sclerosis cross-react with measles and other common virus antigens?
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- How much cash flow does https://scholar.google.com/scholar_lookup?journal=J.%20Immunol.&title=Resident%20and%20infiltrating%20central%20nervous%20system%20APCs%20regulate%20the%20emergence%20and%20resolution%20of%20experimental%20autoimmune%20encephalomyelitis&author=A.E.%20Juedes&author=N.H.%20Ruddle&volume=166&publication_year=2001&pages=5168-5175&pmid=11290800&doi=10.4049/jimmunol.166.8.5168& have monthly?
- How much profit is https://scholar.google.com/scholar_lookup?journal=J.%20Immunol.&title=Prevention%20and%20treatment%20of%20experimental%20autoimmune%20encephalomyelitis%20by%20CNI-1493,%20a%20macrophage-deactivating%20agent&author=J.A.%20Martiney&author=A.J.%20Rajan&author=P.C.%20Charles&author=A.%20Cerami&author=P.C.%20Ulrich&volume=160&publication_year=1998&pages=5588-5595&pmid=9605164& making per month?
- Check the income stats for https://scholar.google.com/scholar_lookup?journal=J.%20Immunol.&title=Immune%20invasion%20of%20the%20central%20nervous%20system%20parenchyma%20and%20experimental%20allergic%20encephalomyelitis,%20but%20not%20leukocyte%20extravasation%20from%20blood,%20are%20prevented%20in%20macrophage-depleted%20mice&author=E.H.%20Tran&author=K.%20Hoekstra&author=N.%20van%20Rooijen&author=C.D.%20Dijkstra&author=T.%20Owens&volume=161&publication_year=1998&pages=3767-3775&pmid=9759903&
- What's the income of https://doi.org/10.1111/j.1365-2249.1995.tb03675.x?
- Income figures for https://scholar.google.com/scholar_lookup?journal=Clin.%20Exp.%20Immunol.&title=Macrophages%20in%20T%20cell%20line-mediated,%20demyelinating,%20and%20chronic%20relapsing%20experimental%20autoimmune%20encephalomyelitis%20in%20Lewis%20rats&author=I.%20Huitinga&author=S.R.%20Ruuls&author=S.%20Jung&author=N.%20Van%20Rooijen&author=H.P.%20Hartung&volume=100&publication_year=1995&pages=344-351&pmid=7743675&doi=10.1111/j.1365-2249.1995.tb03675.x&
- Profit of https://scholar.google.com/scholar_lookup?journal=J.%20Immunol.&title=Treatment%20with%20anti-granulocyte%20antibodies%20inhibits%20the%20effector%20phase%20of%20experimental%20autoimmune%20encephalomyelitis&author=S.R.%20McColl&author=M.A.%20Staykova&author=A.%20Wozniak&author=S.%20Fordham&author=J.%20Bruce&volume=161&publication_year=1998&pages=6421-6426&pmid=9834134&
- How profitable is https://doi.org/10.1016/s0167-5699(99)01512-1?
- Revenue of https://scholar.google.com/scholar_lookup?journal=Immunol.%20Today.&title=Regulation%20of%20T-cell%20responses%20by%20CNS%20antigen-presenting%20cellsdifferent%20roles%20for%20microglia%20and%20astrocytes&author=F.%20Aloisi&author=F.%20Ria&author=L.%20Adorini&volume=21&publication_year=2000&pages=141-147&pmid=10689302&doi=10.1016/s0167-5699(99)01512-1&
- How much income is https://doi.org/10.4049/jimmunol.164.4.1705 earning monthly?
- https://scholar.google.com/scholar_lookup?journal=J.%20Immunol.&title=Functional%20maturation%20of%20adult%20mouse%20resting%20microglia%20into%20an%20APC%20is%20promoted%20by%20granulocyte-macrophage%20colony-stimulating%20factor%20and%20interaction%20with%20Th1%20cells&author=F.%20Aloisi&author=R.%20De%20Simone&author=S.%20Columba-Cabezas&author=G.%20Penna&author=L.%20Adorini&volume=164&publication_year=2000&pages=1705-1712&pmid=10657614&doi=10.4049/jimmunol.164.4.1705&'s total income per month
- What is the earnings of https://doi.org/10.1016/s0165-5728(98)00248-3?
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- How much does https://doi.org/10.1016/s0923-2494(99)80005-4 generate monthly?
- Get to know what's the income of https://scholar.google.com/scholar_lookup?journal=Res.%20Immunol.&title=Immune%20cell%20entry%20to%20the%20CNS-a%20focus%20for%20immunoregulation%20of%20EAE&author=T.%20Owens&author=E.%20Tran&author=M.%20Hassan-Zahraee&author=M.%20Krakowski&volume=149&publication_year=1998&pages=781-789&pmid=9923633&doi=10.1016/s0923-2494(99)80005-4&
- Monthly income for https://doi.org/10.1016/1074-7613(95)90063-2
- https://scholar.google.com/scholar_lookup?journal=Immunity.&title=Blockade%20of%20CD28/B7-1%20interaction%20prevents%20epitope%20spreading%20and%20clinical%20relapses%20of%20murine%20EAE&author=S.D.%20Miller&author=C.L.%20Vanderlugt&author=D.J.%20Lenschow&author=J.G.%20Pope&author=N.J.%20Karandikar&volume=3&publication_year=1995&pages=739-745&pmid=8777719&doi=10.1016/1074-7613(95)90063-2&'s revenue stream
- What is the earnings of https://doi.org/10.1016/0165-5728(95)00008-p?
- https://scholar.google.com/scholar_lookup?journal=J.%20Neuroimmunol.&title=Chemokine%20expression%20in%20murine%20experimental%20allergic%20encephalomyelitis&author=R.%20Godiska&author=D.%20Chantry&author=G.N.%20Dietsch&author=P.W.%20Gray&volume=58&publication_year=1995&pages=167-176&pmid=7539012&doi=10.1016/0165-5728(95)00008-p&'s total income per month
- What's the financial gain of https://doi.org/10.1172/JCI117578?
- Earnings of https://scholar.google.com/scholar_lookup?journal=J.%20Clin.%20Invest.&title=Reversal%20of%20experimental%20autoimmune%20encephalomyelitis%20with%20a%20hydroxamate%20inhibitor%20of%20matrix%20metalloproteases&author=K.%20Gijbels&author=R.E.%20Galardy&author=L.%20Steinman&volume=94&publication_year=1994&pages=2177-2182&pmid=7989572&doi=10.1172/JCI117578&
- What is the earnings of https://doi.org/10.1016/s0165-5728(96)00210-x?
- Earnings of https://scholar.google.com/scholar_lookup?journal=J.%20Neuroimmunol.&title=Matrix%20metalloproteinase%20expression%20during%20experimental%20autoimmune%20encephalomyelitis%20and%20effects%20of%20a%20combined%20matrix%20metalloproteinase%20and%20tumor%20necrosis%20factor-%CE%B1%20inhibitor&author=J.M.%20Clements&author=J.A.%20Cossins&author=G.M.%20Wells&author=D.J.%20Corkill&author=K.%20Helfrich&volume=74&publication_year=1997&pages=85-94&pmid=9119983&doi=10.1016/s0165-5728(96)00210-x&
- https://doi.org/10.4049/jimmunol.164.5.2728 income
- https://scholar.google.com/scholar_lookup?journal=J.%20Immunol.&title=Induction%20of%20chemokine%20secretion%20and%20enhancement%20of%20contact-dependent%20macrophage%20cytotoxicity%20by%20engineered%20expression%20of%20granulocyte-macrophage%20colony-stimulating%20factor%20in%20human%20colon%20cancer%20cells&author=H.%20Shinohara&author=S.%20Yano&author=C.D.%20Bucana&author=I.J.%20Fidler&volume=164&publication_year=2000&pages=2728-2737&pmid=10679114&doi=10.4049/jimmunol.164.5.2728&'s revenue stream
- What's the income generated by https://doi.org/10.1038/84209 each month?
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- What are the earnings of https://scholar.google.com/scholar_lookup?journal=J.%20Neuroimmunol.&title=Acute%20and%20relapsing%20experimental%20autoimmune%20encephalomyelitis%20are%20regulated%20by%20differential%20expression%20of%20the%20CC%20chemokines%20macrophage%20inflammatory%20protein-1%CE%B1%20and%20monocyte%20chemotactic%20protein-1&author=K.J.%20Kennedy&author=R.M.%20Strieter&author=S.L.%20Kunkel&author=N.W.%20Lukacs&author=W.J.%20Karpus&volume=92&publication_year=1998&pages=98-108&pmid=9916884&doi=10.1016/s0165-5728(98)00187-8&?
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