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Title[redir]:
Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die - PMC
Description:
Apoptosis after growth factor withdrawal or drug treatment is associated with mitochondrial cytochrome c release and activation of Apaf-1 and caspase-9. To determine whether loss of Apaf-1, caspase-2, and caspase-9 prevented death of factor-starved ...
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Keywords {š}
caspase, cells, apaf, cell, bcl, apoptosis, death, doi, scholar, pubmed, google, survival, wildtype, withdrawal, absence, lines, growth, factor, cytochrome, clonogenic, ced, fig, clones, independent, cultured, mice, experiments, viability, ligand, pmc, activation, ildependent, determined, fas, show, determine, lacking, agar, flow, cytometry, soft, antibody, number, protection, assays, colonies, plated, marsden, article, release,
Topics {āļø}
org/cgi/content/full/jcb annexin v-fluos/pi staining annexin v-fluos/pi uptake stained plasma membraneāpermeabilized wild-type il-3ādependent cells pmc beta search permit long-term survival mouse-specific antiācaspase-9 il-3ādependent myeloid lines pmc copyright notice short-term protection translated rabbit antiāmouse icad factor-dependent cells responding mouse monoclonal antiācaspase-7 il-3ādependent promyeloid lines fas-ligand blocking antibody bcl-2 provided long-term long-term survival advantage rat monoclonal antiāapaf-1 il-3ādependent cell lines gene-deleted parental clones c-myc transgenic mice enhance long-term survival mouse antiāhuman bcl-2 il-3 withdrawal-induced apoptosis mouse fas ligand growth factorādeprived cells representative wild-type lines fdc-p1 cells publisher site pdf full-length protein worm caenorhabditis elegans tumor suppressor genes methods cell lines fas ligand induction dominant negative fadd long-term protection e14 fetal liver antiāmouse ig fas-induced apoptosis license information pmcid cold spring harbor mice lacking genes cell typeādependent short-term protection p53-dependent apoptosis promyeloid cell lines factor-dependent cells short-term survival provide clonogenic protection
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