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We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC2171557/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC2171557/. The analysis below is for the second page.
Title[redir]:
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death - PMC
Description:
Autophagic degradation of ubiquitinated protein aggregates is important for cell survival, but it is not known how the autophagic machinery recognizes such aggregates. In this study, we report that polymerization of the polyubiquitin-binding protein ...
Title[redir]:
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death - PMC
Description:
Autophagic degradation of ubiquitinated protein aggregates is important for cell survival, but it is not known how the autophagic machinery recognizes such aggregates. In this study, we report that polymerization of the polyubiquitin-binding protein ...
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Keywords {🔍}
cells, protein, bodies, cell, fig, hela, doi, aggregates, pubmed, google, scholar, autophagy, huntingtin, endogenous, structures, mutant, expression, gfpp, domain, sgfpp, proteins, stained, gfplc, uba, cytoplasmic, found, pmc, expressed, formed, transiently, biol, degraded, autophagosomes, confocal, fixed, formation, autophagic, level, live, red, antibodies, bafilomycin, death, article, free, observed, transfected, data, increase, shell,
Topics {✒️}
org/cgi/content/full/jcb wild-type n-httq17 gave redivue pro-mix 35s-methionine flag-tagged nh2-terminal fragment flag-tagged n-httq68 caused transiently expressed flag–n-httq68 nf-kappab activation n-httq68–induced cell death gfp–n-httq68–expressing cells gfp–n-httq68 aggregate surrounded find myc-lc3–positive dots shell surrounding gfp–n-httq68 2w c-apochroma objective gfp-lc3–positive punctuated structures 400-bp ecori–bamhi fragment formvar/carbon-coated grids prostate-derived ets factor dsred-p62 double-positive structure gfp-httq68–transfected hela cells pmc beta search pmc copyright notice shsy-5y neuroblastoma cells membrane-free protein aggregates membrane-free cytosolic structures donkey anti–mouse cy2 multimembrane-bound structure called transiently expressed flag-httq68 late endosomal/lysosomal compartment coexpressing flag–n-httq68 representative gfp–n-httq68 gfp–n-httq68 aggregate expanded polyglutamine-expressing cells pb1 domain–interacting partners oxidative stress-inducible genes 14 μci/ml 35s-methionine antisense rna–mediated depletion stably transfected gfp-p62 aggregated gfp–n-httq68 ectopically expressed gfp-p62 p62-lc3–positive structures observed expressed dsred2-tagged p62 myc-tagged p62 constructs late endosome/lysosomal compartment transiently expressed gfp-p62 ubiquitin/proteasome-mediated degradation gfp-p62 transiently coexpressed huntingtin-induced cell death nh2-terminal pb1 domain gfp-positive cells attached gfp-tagged p62 similar
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