
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Interleukin-23 drives innate and T cellāmediated intestinal inflammation - PMC
Description:
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract involving aberrant activation of innate and adaptive immune responses. We have used two complementary models of IBD to examine the roles of interleukin ...
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Keywords {š}
cells, mice, intestinal, inflammation, pubmed, google, scholar, doi, innate, inflammatory, immune, cell, responses, colitis, cytokine, expression, levels, results, pmc, pathology, disease, fig, prag, recipients, colon, article, svevrag, rag, free, systemic, proinflammatory, intestine, production, hepaticus, role, total, antiilp, isolated, treatment, increased, immunol, control, ilp, spleen, represent, experiments, development, cellmediated, samples, obtained,
Topics {āļø}
sheep antiāratācoated dynabeads cy-chromeāconjugated anti-cd4 antiāil-23p19 monoclonal antibody antiāil-12p40 monoclonal antibodies specific pathogen-free conditions allophycocyanināantiāmouse ifn-γ received antiāil-23p19 lipopolysaccharide-induced airway neutrophilia pmc beta search peāantiāmouse tcrβ vic/tamra-labeled probes percp-conjugated anti-cd4 identifying foxp3-expressing suppressor anti-cd40āinduced colitis pe-conjugated anti-cd25 nonparametric mann-whitney test bacterial live/dead kit ifn-γāsecreting th1 cells allophycocyanin-conjugated anti-cd11b pmc copyright notice hepaticusāinduced innate typhlocolitis 1 mg antiāil-23p19 initial clinical trials cellāmediated colitis correlates th1-dominant chronic colitis q-pcr method based real-time rt-pcr specific il-23p19 subunit interleukin-12-related cytokine transcripts real-time quantitative pcr p35ā/āragā/ā recipients contained cellāmediated systemic inflammation antiāil-23p19 treatment peāantiāmouse il-17 cellādependent inflammatory responses p19ā/āragā/ā recipients showed helicobacter hepaticus-induced colitis pg/mg total protein anti-p19ātreated mice il-12āifn-γ pathways cellāmediated colitis model cellāmediated intestinal inflammation il-23ādriven inflammatory responses il-23p19ā/āragā/ā mice il-23ādriven th17 responses biotinylated antiānk cells publisher site pdf ubiquitous transgenic expression rat monoclonal antibodies il-12/23ādeficient ragā/ā mice
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