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Title[redir]:
CanPredict: a computational tool for predicting cancer-associated missense mutations - PMC
Description:
Various cancer genome projects are underway to identify novel mutations that drive tumorigenesis. While these screens will generate large data sets, the majority of identified missense changes are likely to be innocuous passenger mutations or ...
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Keywords {🔍}
mutations, doi, cancer, google, scholar, pubmed, data, canpredict, application, sift, classifier, protein, gene, methods, change, genes, logrevalue, analysis, snps, page, pmc, algorithm, cancercausing, scores, results, mutation, nlm, cancerassociated, score, goss, search, information, large, polymorphisms, sequence, nonsynonymous, summary, human, ncbi, server, passenger, algorithms, random, tumor, largescale, multiple, samples, science, user, res,
Topics {✒️}
pmc beta search similar tab-delimited format low false-positive rate recent large-scale survey publisher site pdf single nucleotide polymorphisms e-valuevariant/e-valuecanonical nucleic acids res nucleic acids research refseq protein sequences refseq protein sequence matched normal samples median information content consensus coding sequences license information pmcid large-scale annotation tab-delimited format distinguish relevant mutations united states government requires laboratory experimentation wild-type version shiuh-ming luoh alter protein function affect protein function cancer genome projects multiple information sources submitted refseq gene genome-scale screens smaller subsets based protein sequence data providing growth advantages cell line samples dynamic ajax technology ajax call detects implements ajax calls multiple domains covering easily accessible interface distinguishing relevant mutations random forest classifiers batch submission page additional mutations presents large-scale screens large-scale screen gene ontology description pathways underlying cancer statistical geometry methods user-supplied mutations low observed frequency missense mutations joshua machine-learning methods
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