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Title[redir]:
Evidence for an Active Inflammatory Process in the Hibernating Human Myocardium - PMC
Description:
Myocardial hibernation refers to a state of prolonged impairment of left ventricular function in the presence of coronary artery disease, which may be reversed by revascularization. In this study we present evidence for a local inflammatory reaction ...
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Keywords {🔍}
myocardial, segments, cells, pubmed, google, scholar, doi, myocardium, staining, macrophages, recovery, function, mast, figure, inflammatory, expression, dysfunctional, antibody, cell, revascularization, hibernating, newly, mcp, recruited, heart, coronary, mac, macrophage, density, echocardiography, dysfunction, collagen, process, patients, pmc, hibernation, biopsied, mature, monoclonal, fibrosis, macpositive, cellsmm, recruitment, dobutamine, circulation, leukocytes, monocyte, protein, immunohistochemical, active,
Topics {✒️}
high-resolution parallel-hole collimator macrophage-specific antibody pm-2k rest-redistribution thallium-201 tomography rest-redistribution t1–201 tomography transforming growth factor-β identified newly-recruited leukocytes monoclonal antibody pm-2k alkaline phosphatase-based staining alkaline phosphatase-based method pm-2k antibody developed calcium-binding protein mrp14 release preformed tnf-alpha newly recruited leukocytes extravascular mac387-positive cells ischemia-mediated inflammatory process protein-degrading migratory phenotype formalin-fixed kidney specimens pmc beta search differentiated monocyte-derived macrophages monocyte-derived macrophages serve monoclonal anti-tryptase antibody pmc copyright notice methods patient population murine cardiac muscle newly recruited cells end-diastolic wall thickness monoclonal anti-chymase antibody posterior free wall antibody pm-2k mac387-positive leukocytes dual immunohistochemical staining monocyte chemotactic protein-1 calcium-binding myeloid stem cell factor chronic stable angina extracellular matrix proteins left ventricular function peroxidase-based technique newly synthesized mediators mature resident macrophages extracellular matrix metabolism matrix-degrading phenotype peroxidase-based immunohistochemistry transmural myocardial biopsies potent monocyte chemoattractant reversible inflammatory component publisher site pdf repetitive episodic ischemia fibrogenic growth factors license information pmcid
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- Elsasser A, Schaper J: Hibernating myocardium: adaptation or degeneration?
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