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Title[redir]:
Expression of Hypoxia-Inducible Cell-Surface Transmembrane Carbonic Anhydrases in Human Cancer - PMC
Description:
An acidic extracellular pH is a fundamental property of the malignant phenotype. In von Hippel-Lindau (VHL)-defective tumors the cell surface transmembrane carbonic anhydrase (CA) CA9 and CA12 genes are overexpressed because of the absence of pVHL. ...
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Keywords {🔍}
expression, cells, cell, xii, tumors, tumor, google, scholar, pubmed, cancer, doi, tissues, negative, normal, figure, carcinoma, diffuse, focal, renal, ncih, vhl, protein, expressed, human, hypoxia, genes, pmc, lines, shown, glands, carbonic, system, mrna, carcinomas, article, high, ixca, levels, proteins, kidney, observed, lung, table, free, enzymes, immunostaining, gene, breast, ductal, anhydrase,
Topics {✒️}
von hippel-lindau trans-epithelial water movements ubiquitin-proteasome proteolysis system hypoxia-inducible transcription factor pmc beta search proton-linked monocarboxylate transporter voltage-gated proton channels high-resolution measurements reveal mn/ca ix/g250 pmc copyright notice transmembrane carbonic anhydrases negative genito-urinary system human carbonic anhydrases small-cell lung cancer low-grade ductal carcinoma mn/ca ix protein transmembrane carbonic anhydrase squamous/basal cell ca clear cell carcinoma clear cell type publisher site pdf ca ix/ca xii anti-ca xii antibodies hypoxia-inducible factor 1 plausible candidate targets renal cell carcinoma carbonic anhydrase xii carbonic anhydrase deficiencies cell surface membrane necrotic/hypoxic areas showed orchestrates physiological responses blood vessel formation e3 ubiquitin ligases glioblastoma cell line small cell carcinoma carbonic anhydrase gene cell culture conditions renal cell carcinomas vascular permeability factor focal gallbladder/biliary tract license information pmcid mouse monoclonal antibody insect plasma membrane aquaporin water channels cancer cell lines indicating tumor-specific activation cell-surface cas lower respiratory system renal cell cancers tumor cell lines
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