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Title[redir]:
Intrinsic molecular signature of breast cancer in a population-based cohort of 412 patients - PMC
Description:
Molecular markers and the rich biological information they contain have great potential for cancer diagnosis, prognostication and therapy prediction. So far, however, they have not superseded routine histopathology and staging criteria, partly ...
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Ncbi.nlm.nih.gov operates using PLONE.
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Keywords {🔍}
luminal, subtypes, tumors, doi, breast, cancer, therapy, patients, data, erbb, tumor, expression, basallike, clinical, samples, google, scholar, gene, normallike, pubmed, subtype, molecular, genes, cohort, centroid, clustering, adjuvant, group, norwaystanford, swedish, pmc, characteristics, status, grade, correlation, analysis, survival, prognosis, prediction, stockholm, receptor, study, intrinsic, uppsala, file, article, set, kmeans, rna, clustered,
Topics {✒️}
hg-u133ab affymetrix chips worst recurrence-free survival lowest relapse-free survival intravenous cyclophosphamide–methotrexate–5-fluorouracil x-ray tests guided pmc beta search assess low-level processing /support/technical/whitepapers/sadd_whitepaper genome-wide expression patterns lymph-node metastasis status broad population-based cohort biotinylated anti-streptavidin antibody lymph-node positive tumours progression-related signatures based intravenous cmf-based therapy relapse-free survival post-operative adjuvant therapy breast cancer-specific survival average-linkage clustering algorithm k-means clustering methods analyze hormone-adjuvant-treated large population-based cohort relapse-free interval results norway/stanford data competing interests wild-type p53 status van de rijn norway/stanford centroid size fewer er-positive tumors human breast tumours human breast cancers lymph-node metastasis human breast cancer references sorlie lymph-node status primary breast tumors 76 lymph-node-positive license information pmcid early-stage tumors acknowledgments acknowledgements norway/stanford based breast adenocarcinomas based population-based cohorts population-based cohort breast cancer event hormone-based treatments er-positive protein overexpression subsequent primary malignancies increase rna quality rich biological information
Questions {❓}
- Molecular classification and molecular forecasting of breast cancer: ready for clinical application?
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