
NCBI . NLM . NIH . GOV {
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Title[redir]:
Paracrine signaling through the epithelial estrogen receptor α is required for proliferation and morphogenesis in the mammary gland - PMC
Description:
Estradiol is a major regulator of postnatal mammary gland development and thought to exert its effects through estrogen receptor α (ERα) expressed in the mammary gland stroma and epithelium. Previous studies, however, were confounded by the use of ...
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Keywords {🔍}
erα, mammary, doi, epithelium, google, scholar, gland, cells, pubmed, mice, ductal, development, glands, fig, pregnancy, mecs, epithelial, fat, pmc, tissue, shown, signaling, paracrine, mutant, growth, outgrowth, estrogen, receptor, required, proliferation, article, estradiol, females, role, engrafted, recipients, protein, expression, korach, free, proc, natl, stroma, hormones, experiments, estrogens, cleared, gfp, rosa, pads,
Topics {✒️}
c-terminal ligand-binding domain ligand-independent transactivation function quantitative real-time pcr x-gal staining procedure x-gal staining solution ligand-inducible transcription factors single-cell suspensions injected pmc beta search erα-positive tumor develops milk proteins β-casein 129sv/c57bl6 genetic background real-time pcr erα-positive cells acquire publisher site pdf nuclear estrogen receptors x-gal staining estrogen receptor α research molecular oncology army medical research mediating progesterone-induced proliferation nf-κb-ligand rudimentary ductal system erα-positive cells proliferate license information pmcid obvious morphological signs cell growth differ adult mammary gland n-terminal intense hormonal stimulation reconstituted fat pads cleared fat pads wt epithelial grafts including normal functioning tissue structures composed α-lactalbumin forward hormone receptor complexes erα−/− fat pads intracellular fat droplets methods mice relative β-casein region develops substantially β-casein forward contralateral mammary glands epithelial–mesenchymal interactions affect ductal growth [google scholar] 2 [google scholar] 24 tissue reconstitution techniques paracrine growth stimulation kidney capsule concluded
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