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We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC1287974/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC1287974/. The analysis below is for the second page.
Title[redir]:
SUMO modification negatively modulates the transcriptional activity of CREB-binding protein via the recruitment of Daxx - PMC
Description:
Small ubiquitin-like modifier (SUMO) modification is emerging as an important control in transcription regulation. Here, we show that CREB-binding protein (CBP), a versatile transcriptional coactivator for numerous transcription factors in response ...
Title[redir]:
SUMO modification negatively modulates the transcriptional activity of CREB-binding protein via the recruitment of Daxx - PMC
Description:
Small ubiquitin-like modifier (SUMO) modification is emerging as an important control in transcription regulation. Here, we show that CREB-binding protein (CBP), a versatile transcriptional coactivator for numerous transcription factors in response ...
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Keywords {🔍}
cbp, daxx, fig, cells, sumoylation, transcriptional, activity, pubmed, google, scholar, doi, sumo, reporter, transfected, galcbp, hdac, lane, modification, assays, protein, sumoylated, expression, pmc, mutant, cos, vitro, cell, interaction, analysis, supporting, site, results, gene, biol, information, article, nem, subjected, endogenous, transcription, shown, pnas, lysine, chip, construct, antibody, egfpsumo, fragments, free, binding,
Topics {✒️}
4xgal-tk-luc reporter construct p4xgal-tk-luc reporter construct ifn-γ-induced irf1 expression flag-tagged cbp wild-type full-length cbp-3kr failed p5xgal-e1b-luc reporter daxx-mediated repressive effects flag-tagged cbp5 wt gal-driven e1b-promoter gal-driven e1b promoter thermoscript rt-pcr system dual-luciferase assay system p5xgal-e1b-luc constructs pmc beta search flag-tagged cbp wt gal4-fusion heterologous system control gal-dbd-transfected samples flag-tagged cbp fragments sumo-mediated transcriptional repression double egfp-sumo-1 modification gal-cbp wt activated signal-dependent transcription events real-time pcr analyses gst-cbp5 recombinant protein recombinant gst-cbp5 protein quantitative β-gal assays real-time pcr analysis triple egfp-sumo-1 modification transfected flag-cbp wt p4xgal-tk-luc gal-cbp wt conferred gal-cbp fusion protein sumo-dependent transcriptional repression cbp-daxx interaction depends p5xgal-e1b-luc slower-migrating cbp band flag-cbp-transfected 293 cells concomitantly sumo-1-modified cbp901-1100 gal-cbp 3kr conferred heterologous dna-binding domain ifn-γ treatment egfp-sumo-1 conjugation sumoylation-dependent repression mechanism sequence-specific transcription factors diverse signaling events cbp-wt-transfected cells luciferase reporter gene full-length cbp sumo-1-modified cbp fragments endogenous daxx-cbp coimmunoprecipitation
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