
NCBI . NLM . NIH . GOV {
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Title[redir]:
Autophagy in cell death: an innocent convict? - PMC
Description:
The visualization of autophagosomes in dying cells has led to the belief that autophagy is a nonapoptotic form of programmed cell death. This concept has now been evaluated using cells and organisms deficient in autophagy genes. Most evidence ...
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Keywords {🔍}
autophagy, doi, cell, death, scholar, google, pubmed, cells, autophagic, apoptosis, atg, role, pathway, biol, survival, genes, apoptotic, protein, pmc, programmed, degradation, proteins, mitochondrial, free, beclin, mechanism, mitochondria, gene, tumor, article, science, pathways, nutrient, growth, signaling, diseases, bcl, cancer, cellular, evidence, factor, studies, kinase, inhibition, deprivation, human, bax, membrane, starvation, regulation,
Topics {✒️}
tnf-related apoptosis-inducing ligand pi3k/akt/tor signaling pathway etoposide-treated wild-type mefs apg8/12-activating enzyme apg7 voltage-dependent anion channel anti-apoptotic nucleoside analogues gene encoding alpha-synuclein growth factor–deprived bax–/ pressure-overloaded human heart chloroquine-treated cortical neurons pmc beta search low potassium-induced apoptosis blow-fly calliphora vomitoria increased antigen-driven proliferation free fatty acids wild-type α-synuclein breast carcinoma cells toxic stimulus-induced deaths potential pro-death effects τhe protein α-synuclein caspase-dependent cell death sindbis virus–induced apoptosis pmc copyright notice apoptosis-competent cells deprived autophagy gene–dependent death chemotherapy-treated cancer cells α-synuclein gene identified autophagy gene–dependent survival nutrient-sensing signaling pathways established pro-survival effects bax-induced cell death anti-estrogens tamoxifen human breast ovarian staurosporine-induced cell death pathogenic α-synuclein mutants tamoxifen-induced death atg12 enhances starvation-induced autophagy gene–dependent life oncogene-expressing mammary acini tnf-treated human serum-deprived pc12 cells degrading long-lived proteins adult-onset neurodegenerative diseases δ2 glutamate receptor autophagic/lysosomal protein degradation chemotherapy-induced death autophagy-deficient host organisms clearance mechanism cross-talk pi3k signaling pathway yeast autophagy-related genes
Questions {❓}
- Autophagy in cell death: an innocent convict?
- Autophagy: a barrier or an adaptive response to cancer?
- Is autophagy an innocent bystander, a direct death execution pathway, a defense mechanism that ultimately fails in its mission to preserve cell viability, and/or a garbage disposal mechanism that cleans up remnants of a cell already committed to die?
- Mitochondrial disappearance from cells: a clue to the role of autophagy in programmed cell death and disease [review]?
- What is the evidence that autophagy is a death execution mechanism in autophagic cell death?
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- See how much https://doi.org/10.1016/s0300-9084(02)01371-8 makes per month
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- Income figures for https://scholar.google.com/scholar_lookup?journal=Int.%20J.%20Biochem.%20Cell%20Biol.&title=Decreased%20proteolysis%20caused%20by%20protein%20aggregates,%20inclusion%20bodies,%20plaques,%20lipofuscin,%20ceroid,%20and%20%E2%80%9Caggresomes%E2%80%9D%20during%20oxidative%20stress,%20aging,%20and%20disease&author=T%20Grune&author=T%20Jung&author=K%20Merker&author=KJ%20Davies&volume=36&publication_year=2004&pages=2519-2530&pmid=15325589&doi=10.1016/j.biocel.2004.04.020&
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- See how much https://scholar.google.com/scholar_lookup?journal=Hum.%20Mol.%20Genet.&title=Autophagy%20regulates%20the%20processing%20of%20amino%20terminal%20huntingtin%20fragments&author=ZH%20Qin&volume=12&publication_year=2003&pages=3231-3244&pmid=14570716&doi=10.1093/hmg/ddg346& makes per month
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- Discover the revenue of https://doi.org/10.1016/s0896-6273(02)00861-9
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- See how much https://scholar.google.com/scholar_lookup?journal=Nat.%20Rev.%20Microbiol.&title=Cellular%20autophagy:%20surrender,%20avoidance%20and%20subversion%20by%20microorganisms%20%5Breview%5D&author=K%20Kirkegaard&author=MP%20Taylor&author=WT%20Jackson&volume=2&publication_year=2004&pages=301-314&pmid=15031729&doi=10.1038/nrmicro865& makes per month
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