
NCBI . NLM . NIH . GOV {
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Title[redir]:
Extensive Normal Copy Number Variation of a β-Defensin Antimicrobial-Gene Cluster - PMC
Description:
Using a combination of multiplex amplifiable probe hybridization and semiquantitative fluorescence in situ hybridization (SQ-FISH), we analyzed DNA copy number variation across chromosome band 8p23.1, a region that is frequently involved in ...
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Keywords {🔍}
number, copy, google, scholar, pubmed, doi, defb, probes, maph, probe, variation, analysis, human, pmc, dna, genome, accession, article, gene, genet, chromosome, repeat, copies, free, shown, table, sqfish, family, normal, individuals, microsatellite, βdefensin, hybridization, genes, genomic, expression, dosage, βdefensins, duplication, amplifiable, signal, individual, control, families, alleles, data, unit, sequence, results, search,
Topics {✒️}
ddbj/embl/genbank accession number electronic-database information section pulsed-field gel electrophoresis β-defensin antimicrobial-gene cluster β-defensin–cluster copy number fondation jean dausset–ceph olfactory receptor–gene clusters ddbj/embl/genbank databases org/cgi-bin/index anchored oligo-dt primer β-defensin–clustercopy number β-defensin gene cluster dna-based quantitative method pmc beta search analyzing high-density markers pmc copyright notice sfii-digested genomic dna antimicrobial β-defensin genes total-copy-number measurements semiquantitative duplex rt-pcr formamide loading buffer polymerase chain reaction stable deletion/insertion polymorphism high-copy-number allele single-copy subtelomeric regions uk/~pdzjala/maph/maph strong anti-hiv properties maph-determined copy number tailed t-test parameter θ-defensin gene identified ucsc genome bioinformatics reverse-transcriptase reaction β-defensin cluster license information pmcid signal intensity ratios chefiii gel apparatus olfactory repeat regions publisher site pdf β-defensin–clusteralleles share paralogous regions receptor 4–dependent activation human β-defensin 2 human β-defensin-3 web site relative signal ratios copy number variation anti–hiv-1 activity reverse transcriptase blend locus copy number full experimental details
Questions {❓}
- 2: a benign cytogenetic variant?
- 3: a benign variant?
- Tsai CH, Graw SL, McGavran L (2002) 8p23 Duplication reconsidered: is it a true euchromatic variant with no clinical manifestation?
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