
NCBI . NLM . NIH . GOV {
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Title[redir]:
Proinflammatory immune cells disrupt angiogenesis and promote germinal matrix hemorrhage in prenatal human brain - PMC
Description:
Germinal matrix hemorrhage (GMH) is a devastating neurodevelopmental condition affecting preterm infants, but why blood vessels in this brain region are vulnerable to rupture remains unknown. Here we show that microglia in prenatal mouse and human ...
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Keywords {🔍}
cells, fig, data, brain, cell, microglia, human, gmh, iba, immune, mouse, vascular, extended, control, endothelial, doi, pubmed, google, scholar, blood, supplementary, prenatal, cases, samples, images, genes, cortical, min, plate, scrnaseq, subtypes, huvec, pmc, vessels, biological, quantification, article, monocytes, cxcl, video, free, angiogenesis, ges, showed, vzsvz, independent, sections, show, table, performed,
Topics {✒️}
mouse anti-hla-dr + dp + dq multi-subunit ligand–receptor complexes mouse anti-cd1c-pe/cyanine7 unique tgf-β-dependent molecular pecy7-conjugated mouse anti-hcd45 peer review information rat anti-cx3cr1-pe/dazzle 594 mouse anti-cd16-percp cy5 pseudo-bulked scrna-seq data mouse anti-hla-dr-buv395 high-dimensional single-cell mapping scrna-seq ligand–receptor matching code availability main content wild-type pregnant dams predict cell–cell communication online content 1 × 106 cells ml−1in egm-2-mv extensive cell–cell communications light-sheet microscopic imaging 25 mg ml−1texas red dextran acridine orange/propidium iodide author contributions 60–120 mg kg−1and 5–10 mg kg−1 inferring cell–cell communication peer review high-dimensional flow cytometry mouse anti-cd3-bb700 high-resolution interline ccd elane/cxcl16-injected pregnant dams leverage single-cell transcriptomics high-dimensional cytometry analyses footnotes publisher c-fms proto-oncogene facilitate cell–cell communication age-matched control littermates suppress cd45+ cell-mediated dynamic mass-conservation equation competing interests cxcl16-mediated signaling pathways endothelial cell-specific knockout 488 nm solid-state laser fluorescence-activated cell sorting mouse anti-cd45-pecy7 pmc beta search s1pr1fl/fl mice appeared mouse anti-ve–cadherin data availability statement predicted ligand–receptor pairs single-cell transcriptomics data
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Analytics and Tracking {📊}
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