NCBI . NLM . NIH . GOV {
}
We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC11459673/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC11459673/. The analysis below is for the second page.
Title[redir]:
Lysosome–targeting chimeras containing an endocytic signaling motif trigger endocytosis and lysosomal degradation of cell-surface proteins - PMC
Description:
Lysosome–targeting degradation technologies have emerged as a promising therapeutic strategy for the selective depletion of target extracellular and cell-surface proteins by harnessing a cell-surface effector protein such as lysosome–targeting ...
Title[redir]:
Lysosome–targeting chimeras containing an endocytic signaling motif trigger endocytosis and lysosomal degradation of cell-surface proteins - PMC
Description:
Lysosome–targeting degradation technologies have emerged as a promising therapeutic strategy for the selective depletion of target extracellular and cell-surface proteins by harnessing a cell-surface effector protein such as lysosome–targeting ...
Matching Content Categories {📚}
- Science
- Education
- Books & Literature
Content Management System {📝}
What CMS is ncbi.nlm.nih.gov built with?
Custom-built
No common CMS systems were detected on Ncbi.nlm.nih.gov, and no known web development framework was identified.
Traffic Estimate {📈}
What is the average monthly size of ncbi.nlm.nih.gov audience?
🌠 Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
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How Does Ncbi.nlm.nih.gov Make Money? {💸}
We don't see any clear sign of profit-making.
Websites don't always need to be profitable; some serve as platforms for education or personal expression. Websites can serve multiple purposes. And this might be one of them. Ncbi.nlm.nih.gov could be secretly minting cash, but we can't detect the process.
Keywords {🔍}
doi, degradation, tzp, pubmed, google, scholar, signaltacs, tzpp, fig, cells, motif, pmc, lysosomal, pbased, article, internalization, target, free, skov, treatment, signaling, protein, analysis, gga, proteins, trafficking, chem, cell, data, endocytosis, endocytic, azp, sorting, biol, esi, activity, cimpr, pdl, signal, confocal, azpp, tumor, golgi, zhang, potential, pathway, microscopy, results, western, colocalization,
Topics {✒️}
5-[n-ethyl-n-isopropyl]amiloride p3-based anti-pd-l1 signaltacs p1-based anti-pd-l1 signaltacs 1039/d4sc05093b lysosome–targeting chimeras cation-independent mannose-6-phosphate receptor anti-pd-l1 antibody approved adp-ribosylation factor-binding proteins p3-based signaltac-mediated degradation signaltac-mediated pd-l1 degradation caveolae/lipid raft-dependent endocytosis treating pd-l1-positive cells including proteolysis-targeting chimeras p1-based her2-targeting signaltacs az-p3 degraded pd-l1 newly synthesized mannose-6-phosphate dileucine-based sorting signal tyrosine-based endocytosis signal tz-p2-p1 predominantly occurred p3-based signaltacs mediate tz-p3-mediated protein degradation approved anti-her2 antibody tyrosine-based signal tag pmc beta search lysosome–targeting signaling tag dileucine-based signaling motif lysosome-directed protein effector signaltac-mediated degradation strategy lysosome-targeted protein degradation high-performance liquid chromatography lysosome–targeting chimeras p1-based signaltacs employ low-density lipoprotein receptor tz-p2-p1 rely cell-penetrating peptide linked single endocytic signal internalization-impaired receptor owing signaltac-mediated lysosomal trafficking tyrosine-based signal cell-surface ci-m6pr functions cell-surface pd-l1 ltr-based degraders compete sec-hplc analyses confirmed pd-l1-negative cells lysosome–targeting receptor antibody–peptide fusions cell-surface effector protein tz-p3-mediated degradation mda-mb-231 cells incubated yield tz-p2-p3 mda-mb-231 cells treated
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