
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Mammary stem cells, self-renewal pathways, and carcinogenesis - PMC
Description:
The mammary gland epithelial components are thought to arise from stem cells that undergo both self-renewal and differentiation. Self-renewal has been shown to be regulated by the Hedgehog, Notch, and Wnt pathways and the transcription factor B ...
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Keywords {π}
cells, doi, stem, cell, mammary, signaling, google, scholar, pubmed, selfrenewal, hedgehog, notch, pathway, cancer, human, pathways, wnt, bmi, breast, epithelial, normal, tumor, progenitor, development, gland, differentiation, carcinogenesis, evidence, activation, pmc, shown, role, studies, proteins, nature, tumors, article, mice, ligands, gli, fate, transcription, factor, expression, shh, ptch, Ξ²catenin, dev, free, recently,
Topics {βοΈ}
phenotype esa+cd44+cd25-/lowlineage beta-catenin-independent wnt signaling pmc beta search canonical wnt/Ξ²-catenin pathway dorsal midline cell-fates [google scholar] hennighausen human ras-transformed cells histo-blood group antigen blocking Ξ²-catenin phosphorylation box dna-binding proteins Ξ²-catenin destruction complex steroid receptor-positive cells immunosuppressed nod/scid mice acute promyelocitic leukemia mammosphere-derived culture systems references rudland ps mammosphere-based culture system adenomatous polyposis coli publisher site pdf human proto-oncogene bmi-1 lymphoid enhancer factor/ epithelial-specific antigen promoter binding factor muc-1 glycoprotein calla/cd10 chronic myelogenous leukemia nih grants ca66233 mammary epithelial cells rho-family small gtpases glycogen synthase kinase glycogen synthase kinase-3 mammosphere-derived cells epidermal growth factor multipotent epithelial cells human mammary fibroblasts beta-catenin requires activated Ξ²-catenin results b-cell lymphoma [56] human mammary gland pathway-specific inhibitors cyclopamine license information pmcid mammary stem cells progenitor cells derived ductal dysplasias similar neural stem cells mammary stem cell anchorage-independent conditions 'tumor stem cells' tumor stem cells normal mammary stem showed low levels
Questions {β}
- Is there a neural stem cell in the mammalian forebrain?
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