
NCBI . NLM . NIH . GOV {
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Title[redir]:
STIM1 promotes acquired resistance to sorafenib by attenuating ferroptosis in hepatocellular carcinoma - PMC
Description:
Dysregulated calcium (Ca2+) signaling pathways are associated with tumor cell death and drug resistance. In non-excitable cells, such as hepatocellular carcinoma (HCC) cells, the primary pathway for Ca2+ influx is through stromal interaction ...
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Keywords {π}
cells, stim, doi, sorafenib, cell, hcc, slca, mhcch, ferroptosis, fig, hepb, pubmed, google, scholar, pmc, levels, expression, group, protein, article, cancer, resistance, tumor, free, skf, data, gsh, nfatc, acquired, calcium, inhibitor, staining, soce, usa, treated, death, china, assay, kdhepb, results, significantly, lros, control, role, sensitivity, incubated, western, sfn, nfat, genes,
Topics {βοΈ}
poly-d-lysine round coverslip store-operated calcium entry store-operated ca2+ entry apoptosis inhibitor z-vad-fmk Ξ²-caryophyllene oxide-induced inhibition nfatc2 oe-hek-293t cells real-time quantitative pcr cb17-prkdcscid/l2rgtm1/bcgen atp-binding cassette transporter pathogen-free conditions prior tris-buffered saline tween-20 ensure complete de-esterification pmc beta search ca2+-free buffer solution er-mitochondria ca2+ transfer triple-negative breast cancer cystine transporter slc7a11/xct phosphate-buffered saline tween-20 designed single-guided rna pi3k/akt/nrf2 axis stim1-mediated calcium signaling sr-hcc xenograft model stim1-mediated ca2+ signaling enhanced stim1-mediated soce sr stim1 kd-hep3b stim1 kd-hep3b sr stim1 kd-sr cells sorafenib-induced cell death c11-bodipy probe staining sr-hcc cell models ca2+-free buffer multi-kinase inhibitor stim1-deficient sr cells crispr/cas9 targeted deletion crispr/cas9 technology established acquired sorafenib-resistant mhcc97h-sr cells treated effective anti-tumor therapy transmission electron microscopy mhcc97h-sr cells compared chongqing medical university stim1-mediated soce plays ferroorange fluorescent probe potential nfat-response elements stim1-soce-nfat axis publisher site pdf intracellular calcium pool accelerates metabolic reprogramming transmission electron microscope license information pmcid
Questions {β}
- Calcium signalling and pancreatic cell death: apoptosis or necrosis?
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Analytics and Tracking {π}
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