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Title[redir]:
Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2 - PMC
Description:
The cellular membrane in male meiotic germ cells contains a unique class of phospholipids and sphingolipids that is required for male reproduction. Here, we show that a conserved membrane fluidity sensor, AdipoR2, regulates the meiosis-specific ...
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Keywords {๐}
adipor, doi, fig, mice, pubmed, google, scholar, cell, membrane, pmc, spermatocytes, testis, article, male, data, free, cells, supplementary, meiotic, lipid, testes, germ, elovl, intercellular, defects, telomeres, telomere, seminiferous, tex, protein, scale, nuclear, homologous, source, formation, shown, round, analysis, bridge, cers, bars, spermatids, showed, recombination, chromosome, total, number, expression, vlcpufa, synapsis,
Topics {โ๏ธ}
20โฮผl ez-link sulfo-nhs-lc-biotin single-strand dna-binding protein ultra-long-chain species present dynein-dependent forces applied author contributions dna double-strand breaks signaling molecule sphingosine-1-phosphate competing interests peer review file omega6-polyunsaturated fatty acids simple chloroform-free method formvar-coated copper grids elovl2-dependent vlc-pufa synthesis highly-fluid membrane microenvironment long-chain fatty acids telomere-driven chromosome movements18 double-strand break formation ether lipid-deficient mice34 meiosis-specific protein complex footnotes publisher pmc beta search discussion adipor1/2 meiotic telomere-binding proteins blood-testis barrier dynamics peer review caenorhabditis elegans paqr-2 data availability statements data availability statement adipor1 deficiency-induced suppression major synapsis defectsโunsynapsis license information pmcid transmission electron microscopy ether-lipid-deficient mice testis-specific vlcโpufa testis-specific vlc-pufa meiosis require vlc-pufas meiotic chromosomal dynamics telomere-ne fusion structure mechanism underlying vlc-pufa lipid metabolism-defective mutants cacodylate-buffered glutaraldehyde solution specific chromosomal anomalies testis/body weight ratio meiotic chromosome dynamics strand synthesis system post-meiotic round spermatids jeol jem-1400 stem adipor1/2-elovl2 functional axis 38485951 abstract introduction
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