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Keywords {🔍}

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Topics {✒️}

cation-independent mannose-6-phosphate receptor deliver low-abundance substrates approved integrin-targeting small-molecule [pubmed] [google scholar] randomised placebo-controlled trial related bifunctional conjugates supporting information high-affinity tg2 substrate supplementary materials included enhanced amyloid-β production induce receptor-mediated endocytosis pmc beta search short gluten peptide pmc copyright notice receptor-mediated endocytic mechanisms receptor-mediated endocytic pathway subsequent proteasome-mediated degradation license information pmcid mimicking ac-pqlpf-nh2 enables gluten peptides deregulated egfr signaling peptide binding pockets deamidated gluten peptides tg2 active site dry eye disease α2-macroglobulin representative integrin receptor receptor-mediated endocytosis vitamin b12 receptor pathogenically relevant molecules 100 μg/ml α2m block integrin signaling small molecule ligand sulfo-cy5 fluorophore catalytically active sites bertozzi cr lytacs final edited form amyloid-β oligomers preferred tg2 substrate tg2 substrate/inhibitor abundant active tg2 proteolysis targeting chimeras potential therapeutic utility ac-pqlpf-nh2 tg2/lrp-1 pathway dysregulated integrin activity integrin binding sites antigen presenting cell integrin-targeting drugs lysosomal targeting chimeras

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