
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Bioinformatics-based analysis of the roles of basement membrane-related gene AGRN in systemic lupus erythematosus and pan-cancer development - PMC
Description:
Systemic lupus erythematosus (SLE) is an autoimmune disease involving many systems and organs, and individuals with SLE exhibit unique cancer risk characteristics. The significance of the basement membrane (BM) in the occurrence and progression of ...
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Keywords {🔍}
doi, agrn, expression, pubmed, google, scholar, analysis, sle, genes, article, figure, pmc, cancer, immune, free, cell, cells, patients, correlation, lupus, feature, tumor, systemic, bmrelated, infiltration, basement, erythematosus, tissues, data, disease, model, diagnostic, expressed, gene, development, study, role, significantly, membrane, zhang, pancancer, progression, research, protein, gsea, type, survival, agrin, showed, open,
Topics {✒️}
wnt/beta-catenin signaling pathway mir-363-3p-spock2 axis cross-sectional population-based study congenital myasthenic syndrome pmc beta search βig-h3/tgf-βi grade ii/iii gliomas basophil activation-dependent autoantibody ethics statement cell-autonomous signal transmitted pi3k-akt signaling pathway perform kaplan-meier analysis gov/geo/query/acc agrin-deficient mutant mice long-term followup study data availability statements progression-free interval cd4 t-cell memory svm-rfe results show subsequent pan-cancer analysis basement membrane laminin spock2 high-expression subgroup functional gene annotation neural stem/progenitor cells human immune-related diseases specific biological processes colq low-expression subgroup col4a3 low-expression subgroup bm-related genes play phf13 low-expression subgroup colq high-expression subgroup agrn high-expression subgroup svm–rfe algorithm selection survival characteristics showed tgfbi high-expression subgroup diabetes-risk gene based differentially expressed genes kegg enrichment analysis glomerular basement membrane pi3k-akt pathway function primarily focuses pi3k/akt pathway tumor-infiltrating immune cells receptor signaling pathway degradation predicts response performed pan-cancer analysis tumor mutation burden machine learning methods guides cell polarity chemokine signaling pathway
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