CRAN . RSTUDIO . COM {}

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We are analyzing https://cran.rstudio.com/web/packages/mulea/index.html.

Title:
CRAN: Package mulea
Description:
Background - Traditional gene set enrichment analyses are typically limited to a few ontologies and do not account for the interdependence of gene sets or terms, resulting in overcorrected p-values. To address these challenges, we introduce mulea, an R package offering comprehensive overrepresentation and functional enrichment analysis. Results - mulea employs a progressive empirical false discovery rate (eFDR) method, specifically designed for interconnected biological data, to accurately identify significant terms within diverse ontologies. mulea expands beyond traditional tools by incorporating a wide range of ontologies, encompassing Gene Ontology, pathways, regulatory elements, genomic locations, and protein domains. This flexibility enables researchers to tailor enrichment analysis to their specific questions, such as identifying enriched transcriptional regulators in gene expression data or overrepresented protein domains in protein sets. To facilitate seamless analysis, mulea provides gene sets (in standardised GMT format) for 27 model organisms, covering 22 ontology types from 16 databases and various identifiers resulting in almost 900 files. Additionally, the muleaData ExperimentData Bioconductor package simplifies access to these pre-defined ontologies. Finally, mulea
Website Age:
27 years and 1 months (reg. 1998-05-15).

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Education
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Custom-built

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🚀 Good Traffic: 50k - 100k visitors per month

Based on our best estimate, this website will receive around 71,447 visitors per month in the current month.

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How Does Cran.rstudio.com Make Money? {💸}

We can't see how the site brings in money.

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Keywords {🔍}

mulea, aut, ontologies, enrichment, analysis, gene, package, muleatgz, traditional, sets, diverse, protein, muleazip, rrelease, roldrel, false, discovery, rate, terms, resulting, functional, results, progressive, efdr, biological, data, tools, ontology, domains, researchers, questions, gmt, model, organisms, files, sources, cran, rcpp, tamas, stirling, balazs, citation, source, binaries, arm, multiple, background, set, analyses, typically,

Topics {✒️}

/eltebioinformatics/mulea/issues license functional enrichment analysis encompassing gene ontology tailor enrichment analysis gene expression data overcorrected p-values leila gul [aut] gz windows binaries facilitate seamless analysis /eltebioinformatics/mulea needscompilation diverse research areas flexibility enables researchers standardised gmt format interconnected biological data mulea results documentation mulea archive linking diverse biological questions org/package=mulea pre-defined ontologies user-defined ontologies overrepresented protein domains zip macos binaries canonical form https news cran checks enrichment analysis traditional tools gene sets progressive efdr protein domains diverse ontologies specific questions offers researchers protein sets package source introduce mulea mulea expands conclusions - mulea mulea fosters mulea author typically limited specifically designed wide range regulatory elements genomic locations 27 model organisms easy integration gmt files flexible toolkit addressing limitations model organisms

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4.9s.