
NCBI . NLM . NIH . GOV {
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Title[redir]:
Intraductal xenografts show lobular carcinoma cells rely on their own extracellular matrix and LOXL1 - PMC
Description:
Invasive lobular carcinoma (ILC) is the most frequent special histological subtype of breast cancer, typically characterized by loss of Eâcadherin. It has clinical features distinct from other estrogen receptorâpositive (ER+) breast cancers but the ...
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Keywords {đ}
cells, fig, ilc, tumor, cell, google, scholar, pubmed, doi, expression, breast, cancer, lobular, pmc, xenografts, article, sum, free, growth, loxl, analysis, intraductal, mice, glands, models, mammary, carcinoma, invasive, gene, data, treatment, ilcs, bapn, ecm, months, appendix, lines, injection, nonilc, line, shloxl, molecular, disease, showed, showing, genes, human, metastatic, signaling, mcf,
Topics {âď¸}
ch/labs/briskenâlab/preclinicalmodelcourse/ https ch/labs/briskenâlab/ https de la monte cgâprkdcscid il2rgtm1wjl/szj pmc beta search deâdifferentiated cellular state disseminated mcf7âluc2âgfp cells lobular carcinoma cellâintrinsic natural compound βâaminopropionitrile sexâlinked skeletal phenotype lobular carcinomaâspecific trait gov/geo/query/acc cell populationâspecific functions tumor cellâintrinsic characteristic 5 Οg/ml deoxyribonuclease dnaase induce humanâspecific structures world medical associationâdeclaration patientâderived carcinoma cells rnaâseq data produced tumor cellâderived rnas patientâderived tumor cells tumor cellâintrinsic feature cellâcell communication genes patientâderived intraductal xenografts rnaâseq read counts genomeâwide transcriptomic analysis reisâfilho js rfpâluc2 tumor cells generating doubleâstranded cdna ďż˝srcâdependent sustained activation realâtime pcr analysis multifocal epithelial tumors rfpâluciferase expressing lentiviruses semi qrtâpcr normalized mixedâeffects linear models ďż˝cadherinâ carcinomaâderived mm134 sum44âluc2ârfp cells subjected tumorâbearing mice resulting doubleâstranded cdna mdaâmbâ134âvi cells mm134ârfp/luc2 cells ilcâspecific transcriptional signature synthetic lethal vulnerabilities gfp/rfp signal emanating logâtransformed luminescence ¹ sem representative fluorescent stereoâmicrographs gfp/rfp positive gland embo mol med epithelialâepithelial interactions lobularâspecific molecular characteristics
Questions {â}
- Guiu S, Wolfer A, Jacot W, Fumoleau P, Romieu G, Bonnetain F, Fiche M (2014) Invasive lobular breast cancer and its variants: how special are they for systemic therapy decisions?
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