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Title:
Movement of myosin-coated fluorescent beads on actin cables in vitro | Nature
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Myosin-coated fluorescent beads are observed to move unidirectionally along organized actin filament arrays in the alga, Nitella, with an average velocity similar to in vivo rates of movement in muscle and other cells. The myosin produces the motive force, as the movement is ATP dependent and is blocked by inactivation of the myosin heads. The movement, which occurs in the absence of bipolar thick filaments, provides a quantitative assay for myosin motility.
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nature portfolio permissions reprints privacy policy myosin-coated fluorescent beads advertising social media subscribe nature japan nature 173 nature 299 nature 233 nature 243 nature 303 nature single-molecule biophysics carlos cold spring harb bipolar thick filaments personal data gliding actin filament springerlink instant access data protection permissions average velocity similar privacy actin bundles driven single unlabelled proteins explore content subscription content european economic area institutional subscriptions read cross-bridge mechanisms sherman fairchild building super-resolution imaging accepting optional cookies myosin produces myosin heads myosin motility journals search log direct optical sensing manage preferences connecticut health center article purchase article sheetz access content article cite issue learn stanford university school usa michael vitro michael
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