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Title:
Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens - PubMed
Description:
Many tumors express tumor-specific antigens capable of being presented to CD8+ T cells by major histocompatibility complex (MHC) class I molecules. Antigen presentation models predict that the tumor cell itself should present these antigens to T cells. However, when conditions for the priming of tum …
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Keywords {🔍}
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Topics {✒️}
bone marrow-derived cells similar articles cited main page content / immunology melanoma major histocompatibility complex literature sources tumor antigens exogenous antigens tumor-specific responses antigens class united states government antitumour immune responses dc-targeting lentivectors newly diagnosed glioblastoma naked plasmid dna ciba found symp prognostic survival biomarkers tumor cell cells cancer immunol immunother cited inbred balb 7513904 abstract abstract present tumor vaccines tumor microenvironment cell function pubmed wordmark pubmed logo mhc ctl priming plasmid dna human services hhs detectable presentation cross-presentation cancer immunotherapy immunother adv official website efficiently transferred previously thought lee dj carson da exp med lymphocytes intramuscular immunization walker cm zinkernagel rm
Questions {❓}
- Does B7-1 expression confer antigen-presenting cell capacity to tumors in vivo?
- On cross-priming of MHC class I-specific CTL: rule or exception?
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