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Title:
Comparison of live human neutrophil and alveolar macrophage elastolytic activity in vitro. Relative resistance of macrophage elastolytic activity to serum and alveolar proteinase inhibitors - PubMed
Description:
Elastin is an extracellular matrix protein critical to the normal structure and function of human lung. Recently reported data indicate that live human alveolar macrophages can degrade purified elastin in vitro. In this study, we directly compared the elastolytic activity of alveolar macrophages wit …
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Keywords {🔍}
macrophages, human, elastin, pmid, doi, alveolar, pubmed, inhibitors, neutrophils, proteinase, pmc, elastolytic, activity, serum, clin, chapman, cell, free, article, similar, articles, mesh, jci, macrophage, degrade, cells, cathepsin, pulmonary, elastase, review, med, main, ncbi, cited, references, resources, invest, nov, live, neutrophil, vitro, relative, stone, matrix, lung, compared, degraded, breakdown, cysteine, surface,
Topics {✒️}
neutrophil elastase incorporated main page content similar articles cited pulmonary macrophages mesh terms cathepsin pulmonary pathologies] united states government alveolar proteinase inhibitors degrade purified elastin extracellular matrix elastin soluble inhibitors proteinase inhibitors human neutrophils degrade funding linkout human alveolar macrophages noningestible sepharose beads literature sources neutrophils degraded macrophage elastolytic activity similar pattern cathepsin macrophage-mediated pathway live human neutrophil recently reported data inflammatory sites rich rev respir dis nutrition examination survey matrilysin-dependent elastolysis human alveolar fluid inhibitors reilly jj jr elastolytic cysteine proteinase human neutrophils clin climatol assoc lab clin med 7 micrograms elastin/10 elastin breakdown chapman ha jr enzymatically distinct pathways mesh keyword biochem cell biol 6551160 elastin degradation serum-free media alveolar macrophages live macrophages human inflammatory cells human macrophages cited research support macrophages distinct
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