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Identification and utilization of arbitrary correlations in models of recombination signal sequences - PubMed
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Our model-development procedure produces models that estimate well the recombinogenic potential of RSS and are better at RSS recognition than the order zero and order one Markov models. Our models are, therefore, valuable for studying the regulation of both physiologic and aberrant V(D)J recombinati …
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Keywords {🔍}
recombination, doi, pmid, pmc, models, pubmed, genetics, sequence, dna, vdj, free, article, variable, regulatory, figure, nucleic, res, genetic, immunoglobulin, region, states, sequences, sites, rss, physiology, nih, articles, information, order, markov, immunol, acids, gene, variation, aiainiaid, hhsunited, main, ncbi, figures, similar, cited, references, mesh, resources, study, research, nov, signal, methods, positions,
Topics {✒️}
united states government b-lymphocyte gene rearrangement funding linkout t-cell antigen-receptor genes genetic variation main page content markov chains molecular population genetics similar articles cited hhs computational tools software variation b-cell articles references mitchison highly variable high-throughput recombination assays lymphocytes similar articles dna regulatory sites markov models signal-length sequence develop methods algorithmical methods sequence comparison reveals understanding sequence variability sequence-dependent dynamics protein-binding sites nucleic acids res regulatory dna enhanced genome annotation recombination signal sequences coding gene segments prior empirical evidence information score genomic inserts contribute de la rosa yeast saccharomyces cerevisiae research support measured recombination efficiencies mutual information human antibody diversity produces models individual nucleotide positions figures pubmed vanet pubmed show pubmed wordmark pubmed logo spacer sequence sequence interposed
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