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nature portfolio semi-synthetic k48-linked di-ubs privacy policy ube2k–ub/e3/polyub reveals mechanisms mutant k48-linked di-ubs branched k29/k48-linked chain k29/k48-linked branched chain k29-linked di-ubiquitin chain ubiquitylating k48-linked di-ubs form k29/k48-branched polyubiquitination k29/k48-linked branched chains ubr1-mediated n-degron polyubiquitination advertising european research council k29/k48-branched ubiquitin chains k48/k63-branched ubiquitin chains k48-linked di-ub chain 5 mm isopropyl β-d-thiogalactopyranoside k48-linked di-ub substrate febs open bio testing k48-linked di-ubs e6-ap ubiquitin-protein ligase ub1–75–intein–chitin binding domain k48-linked di-ub target intrinsically-disordered n-terminal region social media model-building tools k48-linked chain formation k48-linked di-ub acceptors k29-linked chain formation cryo-em volume post-processing research design horizon 2020 research heterotypic nature generate k48-linked chains k63-ubiquitin chain formation moderate-resolution cryo-em maps k29-linked ubiquitin chain reprints k48-linked ubiquitin chains k48-linked di-ubs cryo-electron microscopy cullin-ring ligase crl2vhl tandem ub-binding regions k29-linked chain produced k29/k48-linked chains hect-type ubiquitin ligases k48-linked di-ub k63-linked ubiquitin chains forms k29-linked branches

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