Here's how NATURE.COM makes money* and how much!

*Please read our disclaimer before using our estimates.
Loading...

NATURE . COM {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Nature.com Make Money
  6. How Much Does Nature.com Make
  7. Keywords
  8. Topics
  9. Schema
  10. Social Networks
  11. External Links
  12. Analytics And Tracking
  13. Libraries
  14. Hosting Providers
  15. CDN Services

We are analyzing https://www.nature.com/articles/s41590-018-0255-3.

Title:
Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation | Nature Immunology
Description:
Recent advances highlight a pivotal role for cellular metabolism in programming immune responses. Here, we demonstrate that cell-autonomous generation of nicotinamide adenine dinucleotide (NAD+) via the kynurenine pathway (KP) regulates macrophage immune function in aging and inflammation. Isotope tracer studies revealed that macrophage NAD+ derives substantially from KP metabolism of tryptophan. Genetic or pharmacological blockade of de novo NAD+ synthesis depleted NAD+, suppressed mitochondrial NAD+-dependent signaling and respiration, and impaired phagocytosis and resolution of inflammation. Innate immune challenge triggered upstream KP activation but paradoxically suppressed cell-autonomous NAD+ synthesis by limiting the conversion of downstream quinolinate to NAD+, a profile recapitulated in aging macrophages. Increasing de novo NAD+ generation in immune-challenged or aged macrophages restored oxidative phosphorylation and homeostatic immune responses. Thus, KP-derived NAD+ operates as a metabolic switch to specify macrophage effector responses. Breakdown of de novo NAD+ synthesis may underlie declining NAD+ levels and rising innate immune dysfunction in aging and age-associated diseases. Macrophages alter their metabolism in response to infection. The authors show that resting macrophages generate nicotinamide adenine dinucleotide via de novo synthesis, but activated and aged cells suppress the rate-limiting enzyme quinolinate phosphoribosyltransferase to regulate mitochondrial and immunological functions.
Website Age:
30 years and 10 months (reg. 1994-08-11).

Matching Content Categories {πŸ“š}

  • Education
  • Science
  • Social Networks

Content Management System {πŸ“}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {πŸ“ˆ}

What is the average monthly size of nature.com audience?

πŸš€πŸŒ  Tremendous Traffic: 10M - 20M visitors per month


Based on our best estimate, this website will receive around 17,334,432 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {πŸ’Έ}


Display Ads {🎯}


The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.

Ads are managed by yourbow.com. Particular relationships are as follows:

Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.com

Reseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.com

How Much Does Nature.com Make? {πŸ’°}


Display Ads {🎯}

$218,500 per month
Our calculations suggest that Nature.com earns between $145,651 and $400,541 monthly online from display advertisements.

Keywords {πŸ”}

article, google, scholar, independent, cas, biologically, humdms, nad, group, samples, test, qprt, macrophages, nature, lps, twotailed, represented, complex, stanford, students, respiration, aged, cell, metabolism, acid, immune, supplementary, young, representative, control, experiments, effect, versus, usa, data, macrophage, novo, mitochondrial, metabolic, access, ido, figure, effects, twoway, anova, pth, analysis, synthesis, immunol, respiratory,

Topics {βœ’οΈ}

Ξ±-amino-Ξ²-carboxymuconate-Ξ΅-semialdehyde decarboxylase nature portfolio journals permissions reprints nature portfolio privacy policy advertising veh-fk866 versus kyb-fk866 veh-veh versus kyn-veh social media kyn-veh versus kyn-fk866 sirt3 steady-state kinetics nature+ nature 478 nature 496 nature 551 nature endogenous tumour-promoting ligand reverse-phase liquid chromatography nad synthesis-breakdown fluxes author information authors cell-driven complement activation regulate macrophage polarization tukey post-hoc test kp-derived nad+ operates permissions sirt3-mediated sod2 activation author correspondence daria mochly-rosen springerlink instant access mesenchymal stem cells restores nad+ levels altered amino acid immune factor generation untargeted metabolomic profiling pth-treated humdms reveals cell-autonomous generation mitochondrial deacetylase sirt3 anti-inflammatory markers cd206 published maps immune cell activation nicotinamide nucleotide synthesis macrophage effector responses sirt3-dependent mechanism privacy nicotinamide adenine dinucleotide subscription content author macrophage metabolic remodeling primary peritoneal macrophages daniel bernstein

Schema {πŸ—ΊοΈ}

WebPage:
      mainEntity:
         headline:Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation
         description:Recent advances highlight a pivotal role for cellular metabolism in programming immune responses. Here, we demonstrate that cell-autonomous generation of nicotinamide adenine dinucleotide (NAD+) via the kynurenine pathway (KP) regulates macrophage immune function in aging and inflammation. Isotope tracer studies revealed that macrophage NAD+ derives substantially from KP metabolism of tryptophan. Genetic or pharmacological blockade of de novo NAD+ synthesis depleted NAD+, suppressed mitochondrial NAD+-dependent signaling and respiration, and impaired phagocytosis and resolution of inflammation. Innate immune challenge triggered upstream KP activation but paradoxically suppressed cell-autonomous NAD+ synthesis by limiting the conversion of downstream quinolinate to NAD+, a profile recapitulated in aging macrophages. Increasing de novo NAD+ generation in immune-challenged or aged macrophages restored oxidative phosphorylation and homeostatic immune responses. Thus, KP-derived NAD+ operates as a metabolic switch to specify macrophage effector responses. Breakdown of de novo NAD+ synthesis may underlie declining NAD+ levels and rising innate immune dysfunction in aging and age-associated diseases. Macrophages alter their metabolism in response to infection. The authors show that resting macrophages generate nicotinamide adenine dinucleotide via de novo synthesis, but activated and aged cells suppress the rate-limiting enzyme quinolinate phosphoribosyltransferase to regulate mitochondrial and immunological functions.
         datePublished:2018-11-26T00:00:00Z
         dateModified:2018-11-26T00:00:00Z
         pageStart:50
         pageEnd:63
         sameAs:https://doi.org/10.1038/s41590-018-0255-3
         keywords:
            Inflammation
            Monocytes and macrophages
            Biomedicine
            general
            Immunology
            Infectious Diseases
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41590-018-0255-3/MediaObjects/41590_2018_255_Fig1_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41590-018-0255-3/MediaObjects/41590_2018_255_Fig2_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41590-018-0255-3/MediaObjects/41590_2018_255_Fig3_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41590-018-0255-3/MediaObjects/41590_2018_255_Fig4_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41590-018-0255-3/MediaObjects/41590_2018_255_Fig5_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41590-018-0255-3/MediaObjects/41590_2018_255_Fig6_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41590-018-0255-3/MediaObjects/41590_2018_255_Fig7_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41590-018-0255-3/MediaObjects/41590_2018_255_Fig8_HTML.png
         isPartOf:
            name:Nature Immunology
            issn:
               1529-2916
               1529-2908
            volumeNumber:20
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group US
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Paras S. Minhas
               affiliation:
                     name:Stanford School of Medicine
                     address:
                        name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
                        type:PostalAddress
                     type:Organization
                     name:Stanford University
                     address:
                        name:Neurosciences Graduate Program, Stanford University, Stanford, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Ling Liu
               affiliation:
                     name:Princeton University
                     address:
                        name:Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, USA
                        type:PostalAddress
                     type:Organization
                     name:Princeton University
                     address:
                        name:Department of Chemistry, Princeton University, Princeton, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Peter K. Moon
               affiliation:
                     name:Stanford School of Medicine
                     address:
                        name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Amit U. Joshi
               url:http://orcid.org/0000-0002-2472-7672
               affiliation:
                     name:Stanford University
                     address:
                        name:Department of Chemical and Systems Biology, Stanford University, Stanford, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Christopher Dove
               affiliation:
                     name:Stanford School of Medicine
                     address:
                        name:Department of Hematology, Stanford School of Medicine, Stanford, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Siddhita Mhatre
               affiliation:
                     name:Stanford School of Medicine
                     address:
                        name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Kevin Contrepois
               url:http://orcid.org/0000-0001-9678-5161
               affiliation:
                     name:Stanford School of Medicine
                     address:
                        name:Department of Genetics, Stanford School of Medicine, Stanford, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Qian Wang
               affiliation:
                     name:Stanford School of Medicine
                     address:
                        name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Brittany A. Lee
               affiliation:
                     name:Stanford School of Medicine
                     address:
                        name:Department of Genetics, Stanford School of Medicine, Stanford, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Michael Coronado
               affiliation:
                     name:Stanford School of Medicine
                     address:
                        name:Department of Pediatrics, Stanford School of Medicine, Stanford, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Daniel Bernstein
               affiliation:
                     name:Stanford School of Medicine
                     address:
                        name:Department of Pediatrics, Stanford School of Medicine, Stanford, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Michael P. Snyder
               affiliation:
                     name:Stanford School of Medicine
                     address:
                        name:Department of Genetics, Stanford School of Medicine, Stanford, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Marie Migaud
               affiliation:
                     name:University of South Alabama
                     address:
                        name:Mitchell Cancer Institute, University of South Alabama, Mobile, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Ravindra Majeti
               affiliation:
                     name:Stanford School of Medicine
                     address:
                        name:Department of Hematology, Stanford School of Medicine, Stanford, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Daria Mochly-Rosen
               url:http://orcid.org/0000-0002-6691-8733
               affiliation:
                     name:Stanford University
                     address:
                        name:Department of Chemical and Systems Biology, Stanford University, Stanford, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Joshua D. Rabinowitz
               affiliation:
                     name:Princeton University
                     address:
                        name:Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, USA
                        type:PostalAddress
                     type:Organization
                     name:Princeton University
                     address:
                        name:Department of Chemistry, Princeton University, Princeton, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Katrin I. Andreasson
               url:http://orcid.org/0000-0001-8391-4155
               affiliation:
                     name:Stanford School of Medicine
                     address:
                        name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
                        type:PostalAddress
                     type:Organization
                     name:Stanford University
                     address:
                        name:Stanford Neuroscience Institute, Stanford University, Stanford, USA
                        type:PostalAddress
                     type:Organization
                     name:Stanford University
                     address:
                        name:Stanford Immunology Program, Stanford University, Stanford, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation
      description:Recent advances highlight a pivotal role for cellular metabolism in programming immune responses. Here, we demonstrate that cell-autonomous generation of nicotinamide adenine dinucleotide (NAD+) via the kynurenine pathway (KP) regulates macrophage immune function in aging and inflammation. Isotope tracer studies revealed that macrophage NAD+ derives substantially from KP metabolism of tryptophan. Genetic or pharmacological blockade of de novo NAD+ synthesis depleted NAD+, suppressed mitochondrial NAD+-dependent signaling and respiration, and impaired phagocytosis and resolution of inflammation. Innate immune challenge triggered upstream KP activation but paradoxically suppressed cell-autonomous NAD+ synthesis by limiting the conversion of downstream quinolinate to NAD+, a profile recapitulated in aging macrophages. Increasing de novo NAD+ generation in immune-challenged or aged macrophages restored oxidative phosphorylation and homeostatic immune responses. Thus, KP-derived NAD+ operates as a metabolic switch to specify macrophage effector responses. Breakdown of de novo NAD+ synthesis may underlie declining NAD+ levels and rising innate immune dysfunction in aging and age-associated diseases. Macrophages alter their metabolism in response to infection. The authors show that resting macrophages generate nicotinamide adenine dinucleotide via de novo synthesis, but activated and aged cells suppress the rate-limiting enzyme quinolinate phosphoribosyltransferase to regulate mitochondrial and immunological functions.
      datePublished:2018-11-26T00:00:00Z
      dateModified:2018-11-26T00:00:00Z
      pageStart:50
      pageEnd:63
      sameAs:https://doi.org/10.1038/s41590-018-0255-3
      keywords:
         Inflammation
         Monocytes and macrophages
         Biomedicine
         general
         Immunology
         Infectious Diseases
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41590-018-0255-3/MediaObjects/41590_2018_255_Fig1_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41590-018-0255-3/MediaObjects/41590_2018_255_Fig2_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41590-018-0255-3/MediaObjects/41590_2018_255_Fig3_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41590-018-0255-3/MediaObjects/41590_2018_255_Fig4_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41590-018-0255-3/MediaObjects/41590_2018_255_Fig5_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41590-018-0255-3/MediaObjects/41590_2018_255_Fig6_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41590-018-0255-3/MediaObjects/41590_2018_255_Fig7_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41590-018-0255-3/MediaObjects/41590_2018_255_Fig8_HTML.png
      isPartOf:
         name:Nature Immunology
         issn:
            1529-2916
            1529-2908
         volumeNumber:20
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group US
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Paras S. Minhas
            affiliation:
                  name:Stanford School of Medicine
                  address:
                     name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
                     type:PostalAddress
                  type:Organization
                  name:Stanford University
                  address:
                     name:Neurosciences Graduate Program, Stanford University, Stanford, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Ling Liu
            affiliation:
                  name:Princeton University
                  address:
                     name:Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, USA
                     type:PostalAddress
                  type:Organization
                  name:Princeton University
                  address:
                     name:Department of Chemistry, Princeton University, Princeton, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Peter K. Moon
            affiliation:
                  name:Stanford School of Medicine
                  address:
                     name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Amit U. Joshi
            url:http://orcid.org/0000-0002-2472-7672
            affiliation:
                  name:Stanford University
                  address:
                     name:Department of Chemical and Systems Biology, Stanford University, Stanford, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Christopher Dove
            affiliation:
                  name:Stanford School of Medicine
                  address:
                     name:Department of Hematology, Stanford School of Medicine, Stanford, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Siddhita Mhatre
            affiliation:
                  name:Stanford School of Medicine
                  address:
                     name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Kevin Contrepois
            url:http://orcid.org/0000-0001-9678-5161
            affiliation:
                  name:Stanford School of Medicine
                  address:
                     name:Department of Genetics, Stanford School of Medicine, Stanford, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Qian Wang
            affiliation:
                  name:Stanford School of Medicine
                  address:
                     name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Brittany A. Lee
            affiliation:
                  name:Stanford School of Medicine
                  address:
                     name:Department of Genetics, Stanford School of Medicine, Stanford, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Michael Coronado
            affiliation:
                  name:Stanford School of Medicine
                  address:
                     name:Department of Pediatrics, Stanford School of Medicine, Stanford, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Daniel Bernstein
            affiliation:
                  name:Stanford School of Medicine
                  address:
                     name:Department of Pediatrics, Stanford School of Medicine, Stanford, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Michael P. Snyder
            affiliation:
                  name:Stanford School of Medicine
                  address:
                     name:Department of Genetics, Stanford School of Medicine, Stanford, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Marie Migaud
            affiliation:
                  name:University of South Alabama
                  address:
                     name:Mitchell Cancer Institute, University of South Alabama, Mobile, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Ravindra Majeti
            affiliation:
                  name:Stanford School of Medicine
                  address:
                     name:Department of Hematology, Stanford School of Medicine, Stanford, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Daria Mochly-Rosen
            url:http://orcid.org/0000-0002-6691-8733
            affiliation:
                  name:Stanford University
                  address:
                     name:Department of Chemical and Systems Biology, Stanford University, Stanford, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Joshua D. Rabinowitz
            affiliation:
                  name:Princeton University
                  address:
                     name:Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, USA
                     type:PostalAddress
                  type:Organization
                  name:Princeton University
                  address:
                     name:Department of Chemistry, Princeton University, Princeton, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Katrin I. Andreasson
            url:http://orcid.org/0000-0001-8391-4155
            affiliation:
                  name:Stanford School of Medicine
                  address:
                     name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
                     type:PostalAddress
                  type:Organization
                  name:Stanford University
                  address:
                     name:Stanford Neuroscience Institute, Stanford University, Stanford, USA
                     type:PostalAddress
                  type:Organization
                  name:Stanford University
                  address:
                     name:Stanford Immunology Program, Stanford University, Stanford, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Nature Immunology
      issn:
         1529-2916
         1529-2908
      volumeNumber:20
Organization:
      name:Nature Publishing Group US
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Stanford School of Medicine
      address:
         name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
         type:PostalAddress
      name:Stanford University
      address:
         name:Neurosciences Graduate Program, Stanford University, Stanford, USA
         type:PostalAddress
      name:Princeton University
      address:
         name:Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, USA
         type:PostalAddress
      name:Princeton University
      address:
         name:Department of Chemistry, Princeton University, Princeton, USA
         type:PostalAddress
      name:Stanford School of Medicine
      address:
         name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
         type:PostalAddress
      name:Stanford University
      address:
         name:Department of Chemical and Systems Biology, Stanford University, Stanford, USA
         type:PostalAddress
      name:Stanford School of Medicine
      address:
         name:Department of Hematology, Stanford School of Medicine, Stanford, USA
         type:PostalAddress
      name:Stanford School of Medicine
      address:
         name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
         type:PostalAddress
      name:Stanford School of Medicine
      address:
         name:Department of Genetics, Stanford School of Medicine, Stanford, USA
         type:PostalAddress
      name:Stanford School of Medicine
      address:
         name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
         type:PostalAddress
      name:Stanford School of Medicine
      address:
         name:Department of Genetics, Stanford School of Medicine, Stanford, USA
         type:PostalAddress
      name:Stanford School of Medicine
      address:
         name:Department of Pediatrics, Stanford School of Medicine, Stanford, USA
         type:PostalAddress
      name:Stanford School of Medicine
      address:
         name:Department of Pediatrics, Stanford School of Medicine, Stanford, USA
         type:PostalAddress
      name:Stanford School of Medicine
      address:
         name:Department of Genetics, Stanford School of Medicine, Stanford, USA
         type:PostalAddress
      name:University of South Alabama
      address:
         name:Mitchell Cancer Institute, University of South Alabama, Mobile, USA
         type:PostalAddress
      name:Stanford School of Medicine
      address:
         name:Department of Hematology, Stanford School of Medicine, Stanford, USA
         type:PostalAddress
      name:Stanford University
      address:
         name:Department of Chemical and Systems Biology, Stanford University, Stanford, USA
         type:PostalAddress
      name:Princeton University
      address:
         name:Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, USA
         type:PostalAddress
      name:Princeton University
      address:
         name:Department of Chemistry, Princeton University, Princeton, USA
         type:PostalAddress
      name:Stanford School of Medicine
      address:
         name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
         type:PostalAddress
      name:Stanford University
      address:
         name:Stanford Neuroscience Institute, Stanford University, Stanford, USA
         type:PostalAddress
      name:Stanford University
      address:
         name:Stanford Immunology Program, Stanford University, Stanford, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Paras S. Minhas
      affiliation:
            name:Stanford School of Medicine
            address:
               name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
               type:PostalAddress
            type:Organization
            name:Stanford University
            address:
               name:Neurosciences Graduate Program, Stanford University, Stanford, USA
               type:PostalAddress
            type:Organization
      name:Ling Liu
      affiliation:
            name:Princeton University
            address:
               name:Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, USA
               type:PostalAddress
            type:Organization
            name:Princeton University
            address:
               name:Department of Chemistry, Princeton University, Princeton, USA
               type:PostalAddress
            type:Organization
      name:Peter K. Moon
      affiliation:
            name:Stanford School of Medicine
            address:
               name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
               type:PostalAddress
            type:Organization
      name:Amit U. Joshi
      url:http://orcid.org/0000-0002-2472-7672
      affiliation:
            name:Stanford University
            address:
               name:Department of Chemical and Systems Biology, Stanford University, Stanford, USA
               type:PostalAddress
            type:Organization
      name:Christopher Dove
      affiliation:
            name:Stanford School of Medicine
            address:
               name:Department of Hematology, Stanford School of Medicine, Stanford, USA
               type:PostalAddress
            type:Organization
      name:Siddhita Mhatre
      affiliation:
            name:Stanford School of Medicine
            address:
               name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
               type:PostalAddress
            type:Organization
      name:Kevin Contrepois
      url:http://orcid.org/0000-0001-9678-5161
      affiliation:
            name:Stanford School of Medicine
            address:
               name:Department of Genetics, Stanford School of Medicine, Stanford, USA
               type:PostalAddress
            type:Organization
      name:Qian Wang
      affiliation:
            name:Stanford School of Medicine
            address:
               name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
               type:PostalAddress
            type:Organization
      name:Brittany A. Lee
      affiliation:
            name:Stanford School of Medicine
            address:
               name:Department of Genetics, Stanford School of Medicine, Stanford, USA
               type:PostalAddress
            type:Organization
      name:Michael Coronado
      affiliation:
            name:Stanford School of Medicine
            address:
               name:Department of Pediatrics, Stanford School of Medicine, Stanford, USA
               type:PostalAddress
            type:Organization
      name:Daniel Bernstein
      affiliation:
            name:Stanford School of Medicine
            address:
               name:Department of Pediatrics, Stanford School of Medicine, Stanford, USA
               type:PostalAddress
            type:Organization
      name:Michael P. Snyder
      affiliation:
            name:Stanford School of Medicine
            address:
               name:Department of Genetics, Stanford School of Medicine, Stanford, USA
               type:PostalAddress
            type:Organization
      name:Marie Migaud
      affiliation:
            name:University of South Alabama
            address:
               name:Mitchell Cancer Institute, University of South Alabama, Mobile, USA
               type:PostalAddress
            type:Organization
      name:Ravindra Majeti
      affiliation:
            name:Stanford School of Medicine
            address:
               name:Department of Hematology, Stanford School of Medicine, Stanford, USA
               type:PostalAddress
            type:Organization
      name:Daria Mochly-Rosen
      url:http://orcid.org/0000-0002-6691-8733
      affiliation:
            name:Stanford University
            address:
               name:Department of Chemical and Systems Biology, Stanford University, Stanford, USA
               type:PostalAddress
            type:Organization
      name:Joshua D. Rabinowitz
      affiliation:
            name:Princeton University
            address:
               name:Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, USA
               type:PostalAddress
            type:Organization
            name:Princeton University
            address:
               name:Department of Chemistry, Princeton University, Princeton, USA
               type:PostalAddress
            type:Organization
      name:Katrin I. Andreasson
      url:http://orcid.org/0000-0001-8391-4155
      affiliation:
            name:Stanford School of Medicine
            address:
               name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
               type:PostalAddress
            type:Organization
            name:Stanford University
            address:
               name:Stanford Neuroscience Institute, Stanford University, Stanford, USA
               type:PostalAddress
            type:Organization
            name:Stanford University
            address:
               name:Stanford Immunology Program, Stanford University, Stanford, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
      name:Neurosciences Graduate Program, Stanford University, Stanford, USA
      name:Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, USA
      name:Department of Chemistry, Princeton University, Princeton, USA
      name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
      name:Department of Chemical and Systems Biology, Stanford University, Stanford, USA
      name:Department of Hematology, Stanford School of Medicine, Stanford, USA
      name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
      name:Department of Genetics, Stanford School of Medicine, Stanford, USA
      name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
      name:Department of Genetics, Stanford School of Medicine, Stanford, USA
      name:Department of Pediatrics, Stanford School of Medicine, Stanford, USA
      name:Department of Pediatrics, Stanford School of Medicine, Stanford, USA
      name:Department of Genetics, Stanford School of Medicine, Stanford, USA
      name:Mitchell Cancer Institute, University of South Alabama, Mobile, USA
      name:Department of Hematology, Stanford School of Medicine, Stanford, USA
      name:Department of Chemical and Systems Biology, Stanford University, Stanford, USA
      name:Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, USA
      name:Department of Chemistry, Princeton University, Princeton, USA
      name:Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, USA
      name:Stanford Neuroscience Institute, Stanford University, Stanford, USA
      name:Stanford Immunology Program, Stanford University, Stanford, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {πŸ‘}(1)

External Links {πŸ”—}(174)

Analytics and Tracking {πŸ“Š}

  • Google Tag Manager

Libraries {πŸ“š}

  • Prism.js
  • Zoom.js

Emails and Hosting {βœ‰οΈ}

Mail Servers:

  • mxa-002c5801.gslb.pphosted.com
  • mxb-002c5801.gslb.pphosted.com

Name Servers:

  • pdns1.ultradns.net
  • pdns2.ultradns.net
  • pdns3.ultradns.org
  • pdns4.ultradns.org
  • pdns5.ultradns.info
  • pdns6.ultradns.co.uk

CDN Services {πŸ“¦}

  • Crossref

4.58s.