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Topics {✒️}

nature portfolio lsab2 streptavidin-peroxidase/sa-hrp kit privacy policy fcr block anti-cd32/cd16 middle-income countries advertising nature 515 nature social media scientific advisory boards anti-mouse pd-l1 apc pd-1/pd-l1 inhibition therapy post-operative anti-pd-l1 author information authors anti-pd-l1 antibody mpdl3280a pd-l1-expressing immune cells reprints single-cell suspension gained sunnybrook research institute worldwide cancer research emt6-cddp tumor-bearing mice original author sponsored research agreement european research council open-label cyclophosphamide-facilitated adoptive immunotherapy high-risk rhabdomyosarcoma pd-1/pd-l1 inhibition host cell pd-l1 continuous low-dose cyclophosphamide promote pd-l1-mediated fisher scientific pan-european expert meeting pd-l1 antibody atezolizumab2 strong anti-metastatic activity anti-pd-l1 antibody metronomic low-dose chemotherapy pd-1-pd-l1 axis toronto research chemicals tumor cell pd-l1 mhc class ii-i pd-l1 antibody blockade pd-l1 antibody therapy erbb2/her2-dependent downregulation anti-pd-l1 groups potent anti-tumor effects sterile phosphate-buffered saline pd-l1 expression increases npj breast cancer daily low-dose ctx

Questions {❓}

• Has the time come for metronomics in low-income and middle-income countries?
• Second, what is the evidence for immunological mechanisms mediating anti-tumor efficacy of the CTX140 1q6d regimen?
• Third, would concomitant use of the immune system boosting CTX140 1q6d regimen improve outcomes of PD-L1 antibody therapy?
• Treating advanced breast cancer with metronomic chemotherapy: what is known, what is new and what is the future?

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